Valsartan/hydrochlorothiazide

Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is an medication used to treat high blood pressure when valsartan is not sufficient.[3] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic.[4] It is taken by mouth.[4]

Valsartan/hydrochlorothiazide
Combination of
ValsartanAngiotensin II receptor antagonist
HydrochlorothiazideThiazide diuretic
Clinical data
Trade namesCo-vasotec, Diovan HCT, Co-Diovan, others
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa611032
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
Identifiers
PubChem CID
KEGG
CompTox Dashboard (EPA)
  (verify)

Common side effects include dizziness and headaches.[4] Serious side effects may include allergic reactions, electrolyte abnormalities, and glaucoma.[1] Use in pregnancy is not recommended.[1]

The combination was approved for medical use in the United States in 1998.[4] It is available as a generic medication.[3] In 2017, it was the 133rd most commonly prescribed medication in the United States, with more than five million prescriptions.[5][6]

References

  1. "Diovan HCT- valsartan and hydrochlorothiazide tablet, film coated". DailyMed. Retrieved 20 January 2021.
  2. https://www.ema.europa.eu/documents/psusa/valsartan-hydrochlorothiazide/valsartan-list-nationally-authorised-medicinal-products-psusa/00010396/202004_en.pdf
  3. British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. p. 179. ISBN 9780857113382.
  4. "Hydrochlorothiazide and valsartan Uses, Side Effects & Warnings". Drugs.com. Retrieved 10 March 2019.
  5. "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
  6. "Hydrochlorothiazide; Valsartan - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.


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