(6-4)DNA photolyase
(6-4)DNA photolyase (EC 4.1.99.13, DNA photolyase, H64PRH, NF-10, phr (6-4), PL-(6-4), OtCPF1, (6-4) PHR, At64PHR) is an enzyme with systematic name (6-4) photoproduct pyrimidine-lyase.[1][2] This enzyme catalyses the following chemical reaction
- (6-4) photoproduct (in DNA) 2 pyrimidine residues (in DNA)
| (6-4)DNA photolyase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.1.99.13 | ||||||||
| CAS number | 37290-70-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is a flavoprotein.
References
- Hitomi K, DiTacchio L, Arvai AS, Yamamoto J, Kim ST, Todo T, Tainer JA, Iwai S, Panda S, Getzoff ED (April 2009). "Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes". Proceedings of the National Academy of Sciences of the United States of America. 106 (17): 6962–7. doi:10.1073/pnas.0809180106. PMC 2678464. PMID 19359474.
- Schleicher E, Hitomi K, Kay CW, Getzoff ED, Todo T, Weber S (February 2007). "Electron nuclear double resonance differentiates complementary roles for active site histidines in (6-4) photolyase". The Journal of Biological Chemistry. 282 (7): 4738–47. doi:10.1074/jbc.m604734200. PMID 17164245.
External links
- (6-4)DNA+photolyase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.