18 Again

• Kim Ha-neul as Jung Da-jung[lower-alpha 3]
  • Han So-eun as 18-year-old Da-jung[4][lower-alpha 4]

Hong Dae-young's wife, 37-year-old mother of twins Shi-ah and Shi-woo, and a JBC intern announcer. Da-jung was very popular among Serim High School boys (she is every male students' first love) and eventually dated her classmate and popular basketball player Hong Dae-young. But before they can complete high school, they had to get married as she got pregnant with Hong Dae-young's twins, delaying her dream job of being a news announcer and postponing her college education. In present time, she is a 37-year-old mother to a pair of teenage twins who were getting fatigued of her husband's behavior. She files for a divorce alongside her job application at JBC to fulfill her dream despite being a mother in her late 30s. She is talented in martial arts, which she demonstrated since she was 18 years old. She gradually became troubled by her attraction towards her twins' 18-year-old friend "Go Woo-young", without knowing that Woo-young was actually her husband whose body reverted back to his 18-year-old self. She later found out Woo-young's true identity and eventually reconciled with her husband when he once again recovered his 37-year-old physical self in the finale of the series.

• Yoon Sang-hyun as Hong Dae-young[lower-alpha 5]

Jung Da-jung's husband, 37-year-old father of twins Shi-ah and Shi-woo, and a senior washing machine repairman. Dae-young was a handsome, popular and talented basketball star in Serim High School. However, he decided not to pursue his basketball career and bravely took responsibility to marry his pregnant classmate and girlfriend Jung Da-jung and be a young father to their twins. In the first years of family life, he struggled to earn money for his family's sustenance, consequently losing his handsome, youthful looks due to combined aging, exhaustion from his multiple jobs, and unhealthy lifestyles like alcohol, smoking, and anger issues. In the present, he is a 37-year-old father to a pair of teenage twins and worked as a senior washing machine repairman for almost 10 years. His life started going downhill when Da-jung files a divorce paper against him and he gets fired from his job by his nepotistic boss.

• Lee Do-hyun as 18-year-old Hong Dae-young turned Go Woo-young[lower-alpha 6]

Wishing he could go back in time and fix his life, Hong Dae-young's 37-year-old body miraculously morphs into his 18-year-old body but retains his 37-year-old mindset and mannerisms. Dae-young starts living a new life as his best friend Go Deok-jin's son "Go Woo-young" and attends Serim High School, his twins' school, as a Class 2-7 student. At first, he wants to fulfill his dream of being basketball star and accepted into college through a basketball scholarship. However, by attending their school, he gets to know things about his twins that he never knew before and, later, the true reason behind the crumbling bond between him and the family. He resolves to use this chance to protect his kids by befriending them and to do his best to be more present to the family despite his appearance as an 18-year-old boy.[lower-alpha 7]

• Roh Jeong-eui as Hong Shi-ah[5][lower-alpha 8]

The older twin daughter of Hong Dae-young and Jung Da-jung; a student of Class 2-7 in Serim High School. A pretty and popular girl at school but with a strong and rebellious personality, she frequently schemes Dae-young for her pocket money. In order to pursue her dream of being a makeup artist, she also works part-time in a convenience store without her parents' permission while only her friends and twin know about this, only to be caught by her father who runs into her while being in his 18-year-old body. Because of the incident in the convenience store, she was hostile towards him, especially when she finds that he (posing as Go Woo-young) is placed in her class, which was aggravated by Woo-young scolding her for her misbehaviour towards her father (without knowing that Woo-young was her father in disguise). However, as the series progressed, she was gradually touched by Woo-young's caring attitude and kindness towards her and start to befriend him, though she later confused Woo-young's kindness as romantic moves (without knowing he is her father). Despite her rebellious nature, she deeply loves and cares about her family, even blaming herself for her parents' crumbling relationship. Because of her late night part-time job, she always comes late to school, and is frequently being seen picking up trash or running in the school field as punishment.

• Ryeoun as Hong Shi-woo[lower-alpha 9]

The younger twin son of Hong Dae-young and Jung Da-jung; a student of Serim High School. Unlike his twin sister and despite his handsome looks, Shi-woo is a school outcast and frequently being bullied by Goo Ja-sung and the basketball team. He is very talented in playing basketball and loves playing it just like Dae-young but he hides this fact from him because he feels inferior with his father's basketball talent. Because of being bullied and his family life, he initially shows a very cold personality and appears mostly in a gloomy mood. He meets his turned-18-year-old father (posing as Go Woo-young) at school when the latter saves him from being bullied by Ja-sung. He became best friends with Woo-young, who protects him from the bullies, plays basketball with him and encourages him to push forward with his basketball career. Through Woo-young, Shi-woo is able to elevate his crumbled self-esteem after being bullied and regain his smile back. He is later accepted into the Hankook University through basketball scholarship, and grown into a popular basketball player with a bright career awaiting him, just like what his father wants when he was younger.

• Kim Mi-kyung as Yeo In-ja

Jung Da-jung's mother. In-ja was very upset with the fact that her daughter was pregnant when she was at school. At first, she wanted Da-jung to abort her twins, but later decided to support her decision in keeping the twins and treating Hong Dae-young like her son. However, she is very upset with Dae-young and Da-jung's decision to divorce without consulting with her. To comfort Da-jung and the twin after her divorce, she lived in Da-jung’s house with her grandson and granddaughter for some time.

• Lee Byung-joon as Hong Joo-man[6]

Hong Dae-young's father who is supportive to Dae-young's basketball career. Eighteen years ago, Joo-man, together with his wife, had kept his wife's failing health a secret from Dae-young in order not to distract him from achieving his basketball career; this makes Dae-young very upset later on when his mother ultimately dies. He aggravated Dae-young's resentment against him when asked Da-jung to abort the pregnancy, which then leads to Dae-young deciding to leave home and live with Da-jung. However, despite the strained relationship between him and Dae-young, he silently supports him through Da-jung by frequently sending her money to support the financially struggling teenage family. He later reconciles with 37-year-old Dae-young at the time when Dae-young's body is still in its 18-year-old form, after Dae-young, who was disguised as Go Woo-young, and emotionally revealed to his father his true self during a meeting between father and son after Woo-young and Shi-woo's basketball match.

• Wi Ha-joon as Ye Ji-hoon[7]

A famous baseball athlete, the pitcher for Seum Wolves. Ji-hoon is well-known and admired by his fans (which includes Dae-young) for his perfect strike-outs. He endorses a number of commercial products, including Go Deok-jin's mobile game. He takes the parenting responsibility of his niece, Ye Seo-yeon after her father (Ji-hoon's elder brother) passed away due to a traffic accident and her mother abandoned the family. He harbors feelings toward Jung Da-jung because she reminds him of his late brother, but later encourages her to reconcile with her husband Dae-young after realising that Da-jung's feelings towards her husband. He is grateful towards Dae-young for saving his niece from the car accident wreckage despite him failing to save his brother on time.

• Kim Kang-hyun as Go Deok-jin[lower-alpha 10]

CEO of the game company Go Go Play; Hong Dae-young's rich best friend. A member of Serim High School's basketball team 18 years ago, Deok-jin became best friends with Dae-young when the latter saved him from their fellow team member Choi Il-kwon's bullying. Just like Hye-in, Deok-jin is also fond of collecting film and game merchandise, and he had built his own success as a game company CEO from his geeky hobby. In present time, he accepts Dae-young in his mansion when the latter leaves home due to his crumbling relationship with Da-jung. When Dae-young's body turns back to its 18-year-old version, he helps Dae-young assume a new identity by posing as his father, naming him "Go Woo-young" and enrolling him at Serim High School in Class 2-7. He falls in love at first sight with Class 2-7's adviser Hye-in during their first encounter at school.

• Lee Mi-do as Choo Ae-rin[lower-alpha 11]

A divorce lawyer; Da-jung's best friend. Eighteen years ago, Ae-rin was smitten with Hong Dae-young and attempted to bully Da-jung for being his girlfriend, unaware of Da-jung being a tough girl who can put up a fight. She became friends with her when Da-jung rescued her from being harassed by their seniors. In the present time, Ae-rin's crush on Dae-young shatters when he lost his handsome looks. She also encourages Da-jung to file the divorce against Dae-young. Her law firm's office is co-located in the same building as Deok-jin's game company office, therefore they always randomly encounter each other.

• Kim Yoo-ri as Ok Hye-in[lower-alpha 12]

A music teacher and the homeroom teacher of Class 2-7 in Serim High School. Hye-in appears to be a beautiful, perfect teacher but she hides her geeky hobby from everyone, even using disguise to go to PC cafe for playing online games. Her secret room is full of film and game merchandise and a computer gaming set. She frequently interacts with a game account that is revealed to be Go Deok-jin's. She slowly develops feelings for Go Deok-jin but due to the fact that he was a father of her newly-transferred student Go Woo-young (who was actually Hong Dae-young who changed back into his teenage self), she politely rejects Deok-jin's feelings until the finale, where Woo-young, who was going to recover his 37-year-old self, confesses to Hye-in that Deok-jin was not his true father and lies that Deok-jin was a kind-hearted stranger who in fact had adopted him when he could not find his birth parents, and encourages her to be together with Deok-jin, which finally allowed Hye-in and Deok-jin to be together.

• Lee Ki-woo as Choi Il-kwon[8]
  • Kim Sun-min as 18-year-old Choi Il-kwon

A PE teacher and basketball coach at Serim High School. Il-kwon was Dae-young, Da-jung, Deok-jin and Ae-rin's classmate in Serim High School 18 years ago; Da-jung was also his first love. During his years in high school, he (and, accidentally, Deok-jin) saw his abusive father paying bribes to their coach in order for him to be included in the main lineup; this leads to him frequently bullying Deok-jin. He also showed a lot of jealousy and insecurity toward Hong Dae-young, in term of both basketball and Da-jung's love. He later copies his coach's crimes in present time, wherein he and his friends from the Hankook University basketball recruitment team collect bribes from the Serim basketball team's parents. He was eventually arrested and sentenced to imprisonment for bribery, along with two of the university coaches he conspired with to collect bribes from the parents.

• Choi Bo-min as Seo Ji-ho[9]
  • Kim Kang-hoon as child Seo Ji-ho

The class president of Class 2-7 in Serim High School. Losing his father at a young age, Ji-ho is the twins' childhood friend, being deeply loved by Dae-young who treats him as his third child. In present time, he is a model student in Serim and he harbors a crush on Hong Shi-ah. Just like Ja-sung, he misunderstands the turned-18-year-old Dae-young's (posing as Go Woo-young) kind and caring behavior towards Hong Shi-ah as romantic moves, a misunderstanding which he held until he found out that Woo-young was actually Shi-ah's father Dae-young, making Ji-ho the only student from Serim to know about Woo-young's true identity. At the end of the series, he attends a medical school after his graduation from high school and became Shi-ah's boyfriend.

• Hwang In-youp as Goo Ja-sung[lower-alpha 13]

A student of Class 2-7 in Serim High School; the captain of Serim's basketball team. Ja-sung is known for his aggressive personality which came from his father, a rich company CEO, who abuses him and his mother, does not believe in his skill in basketball, and pays bribes to Choi Il-kwon. Ja-sung frequently abuses Hong Shi-woo, who once saw him being beaten by his father and consequently made the former very hurt to hide his humiliated side. He tried to show how strong and intimidating he is, but actually he is a weak-hearted and insecure person. He slowly harbors feelings for Hong Shi-ah and tries to win her heart even though she dislikes him because of her bullied twin and another past incident where Ja-sung insulted her mother (who just became an announcer at JBC at that time). With the help of turned-18-years-old Dae-young (posing as Go Woo-young), he drops his aggressiveness and insecurity and starts forgiving his father, apologizing and befriending Shi-woo. However, he maintain a bit of hostility towards Woo-young because he misunderstands Woo-young's kindness to Shi-ah as making romantic moves on her. He later confesses his feelings to Shi-ah (with Woo-young's help), but Shi-ah, due to her remembering Ja-sung's bullying behaviour towards Shi-woo in the past, politely declined his offer to date her and maintains a neutral relationship together with him throughout the rest of the series.

• Oh So-hyun as Jeon Bo-bae

A student of Class 2-7 in Serim High School; one of Hong Shi-ah's friends. Bo-bae harbors a crush on Go Woo-young and confesses to him, but she stops pursuing him when she mistakenly assumes he likes Hong Shi-ah.

• Lee Eun-jae as Uhm So-mi

A student of Class 2-7 in Serim High School; one of Hong Shi-ah's friends. Without Shi-ah's knowing, So-mi has crush on her twin brother Hong Shi-woo and tries to confess to her feelings to him.

• Ryu Da-bin as Hwang Young-sun

A student of Class 2-7 in Serim High School; one of Hong Shi-ah's friends.

• Bin Chan-wook as Bang Ki-yong

A student of Class 2-7 in Serim High School; Ja-sung's friend and fellow basketball player who also bullies Shi-woo. His father also bribes Choi Il-kwon so he can play in official games. It is presumed that he, like Ja-sung, began to befriend Si-woo and apologises to him for bullying him in the past.

• Jang Hyuk-jin as Heo Woong-gi

Manager of the announcer department at JBC. Despite his reluctance, Woong-gi is ordered by the Director to do anything he can to make Jung Da-jung quit the internship.

• Ahn Nae-sang as Moon Sang-hwi

Director of JBC News. A prejudiced senior, Sang-hwi dislikes the fact that Jung Da-jung passed the blind test and has been accepted as an intern despite being a mother in her thirties, and a teenage mother at that. He initially orders Woong-gi to make Da-jung quit the internship during her probation period, but he becomes fond of her due to the skills and talent she manifests at work. He later regrets his prejudice against Da-jung after she left the company.

• Kim Yoon-hye as Kwon Yu-mi[10]

One of the four intern announcers (which includes Da-jung) at JBC. Yu-mi is the youngest among the interns and she always feels threatened by Da-jung's existence in the company, and viewed her and the other interns as rivals. However, after Da-jung saved her in an incident, she tried to repay her and successfully let her return to work in JBC after she was expelled from the company, and she grew to become more amicable towards her colleagues after this incident.

• Ko Eun-min as Lim Ja-young

One of the four intern announcers at JBC. Ja-young is friendly towards Da-jung and Gi-tae and is annoyed at Yu-mi's conceit and sense of competition towards them.

• Yang Dae-hyuk as Nam Gi-tae

One of the four intern announcers at JBC. Gi-tae is the only male intern among the four.

• Ahn Mi-na as Choi Ji-na

An announcer at JBC who is Yu-mi's senior.

• Kim Yeon-jeong and Moon Woo-bin as Go Go Play employees

Go Deok-jin's subordinates. They are chance witnesses in awkward scenes involving Deok-jin, the turned-18-year-old Dae-young (posing as Woo-young) and Ae-rin, which leads to them mistakenly thinking that Woo-young is a severely disrespectful son, that Deok-jin is an irresponsible father, and that Ae-rin is Deok-jin's lover.

• Jun Hyun-moo as Bae Seung-hyun (Ep. 2)

One of the evaluators during the announcer casting blind test at JBC.

• Jang Sung-kyu as himself (Ep. 2)

An applicant during the announcer casting at JBC

• Im Ji-kyu as Ji-hoon's older brother
• Hur Jae as Coach at 2009 KBU draft (Ep. 8)[11]
• Heo Jung-min as Ae-rin's ex-boyfriend
• Cho Ryeon as Dae-young's biological mother
• Lee Eol as Il-kwon's father
• Do Won-kyung as a Serim High School graduate and singer
• Kim Dong-hyun as a self-defense trainer (Ep. 10)
• Moon Ji-in as a wife in Couples in Crisis (Ep. 11)
• Heo Jae-ho as a husband in Couples in Crisis (Ep. 11)
• Kim Ho-chang as a husband in Couples in Crisis (Ep. 11)

The drama's soundtrack is compiled in a two-part album released in 10 November 2020. CD 1 and CD 2 contain the drama's theme songs and musical score, respectively.[30][31]