3,3'-Diiodothyronine

3,3'-Diiodothyronine, also known as 3,3'-T2, is a metabolite of thyroid hormone.

3,3'-Diiodothyronine
Names
IUPAC name
2-Amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3-iodo-phenyl]propanoic acid
Other names
O-(4-Hydroxy-3-iodophenyl)-3-iodotyrosine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
MeSH 3,3'-diiodothyronine
Properties
C15H13I2NO4
Molar mass 525.077 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

It is formed from the breakdown of triiodothyronine. Levels can be affected in certain disease states.[1]

Reactions

Synthesis of T2 from T3, and from reverse T3

References

  1. Pinna G; Hiedra L; Meinhold H; et al. (September 1998). "3,3'-Diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors and of healthy subjects during acute stress". J. Clin. Endocrinol. Metab. 83 (9): 3071–7. doi:10.1210/jc.83.9.3071. PMID 9745405.
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