4-(dimethylamino)phenylazoxybenzene reductase
In enzymology, a 4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction
- 4-(dimethylamino)phenylazobenzene + NADP+ 4-(dimethylamino)phenylazoxybenzene + NADPH + H+
| 4-(dimethylamino)phenylazoxybenzene reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.7.1.11 | ||||||||
| CAS number | 103843-39-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are 4-(dimethylamino)phenylazobenzene and NADP+, whereas its 3 products are 4-(dimethylamino)phenylazoxybenzene, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-(dimethylamino)phenylazobenzene:NADP+ oxidoreductase. Other names in common use include N,N-dimethyl-p-aminoazobenzene oxide reductase, dimethylaminoazobenzene N-oxide reductase, NADPH-dependent DMAB N-oxide reductase, and NADPH:4-(dimethylamino)phenylazoxybenzene oxidoreductase.
References
- Lashmet Johnson PR, Ziegler DM (1986). "Properties of an N,N-dimethyl-p-aminoazobenzene oxide reductase purified from rat liver cytosol". J. Biochem. Toxicol. 1 (1): 15–27. doi:10.1002/jbt.2570010104. PMID 3152268.