AK3

AK3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1ZD8
Identifiers
Aliases	AK3, AK3L1, AK6, AKL3L, AKL3L1, FIX, adenylate kinase 3
External IDs	OMIM: 609290 MGI: 1860835 HomoloGene: 21744 GeneCards: AK3
Gene location (Human)
Chr.	Chromosome 9 (human)[1]
End	4,742,043 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	29,047,961 bp[2]
Gene ontology
Molecular function	• transferase activity; • nucleotide binding; • nucleobase-containing compound kinase activity; • GTP binding; • ATP binding; • GO:0001948 protein binding; • phosphotransferase activity, phosphate group as acceptor; • kinase activity; • nucleoside triphosphate adenylate kinase activity; • adenylate kinase activity;
Cellular component	• mitochondrial matrix; • mitochondrion;
Biological process	• UTP metabolic process; • blood coagulation; • nucleobase-containing compound metabolic process; • phosphorylation; • AMP metabolic process; • GTP metabolic process; • ITP metabolic process; • nucleoside monophosphate phosphorylation; • ADP biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	50808
	56248
	ENSG00000147853
	ENSMUSG00000024782
	Q9UIJ7
	Q9WTP7
NM_016282; NM_001199852; NM_001199853; NM_001199854; NM_001199855;
	NM_001199856
	NM_021299; NM_001365071
	NP_001186781; NP_001186782; NP_001186784; NP_001186785; NP_057366
	NP_067274; NP_001352000
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene. [5]

Function

The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene.

References

GRCh38: Ensembl release 89: ENSG00000147853 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000024782 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Adenylate kinase 3". Retrieved 2017-05-19.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human GTP:AMP phosphotransferase AK3, mitochondrial (AK3)

AK3

Function

References

External links

Further reading