ANAPC11

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.[5][6]

ANAPC11
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesANAPC11, APC11, Apc11p, HSPC214, anaphase promoting complex subunit 11
External IDsOMIM: 614534 MGI: 1913406 HomoloGene: 41136 GeneCards: ANAPC11
Gene location (Human)
Chr.Chromosome 17 (human)[1]
Band17q25.3Start81,890,790 bp[1]
End81,900,991 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51529

66156

Ensembl

ENSG00000141552

ENSMUSG00000025135

UniProt

Q9NYG5

Q9CPX9

RefSeq (mRNA)

NM_001038230
NM_025389

RefSeq (protein)

NP_001033319
NP_079665

Location (UCSC)Chr 17: 81.89 – 81.9 MbChr 11: 120.6 – 120.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

ANAPC11 has been shown to interact with ANAPC2[7][8] and CDC27.[5][9]

References

  1. GRCh38: Ensembl release 89: ENSG00000141552 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025135 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM (Sep 2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex". Proc Natl Acad Sci U S A. 97 (16): 8973–8. Bibcode:2000PNAS...97.8973G. doi:10.1073/pnas.97.16.8973. PMC 16806. PMID 10922056.
  6. "Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast)".
  7. Tang, Z; Li B; Bharadwaj R; Zhu H; Ozkan E; Hakala K; Deisenhofer J; Yu H (Dec 2001). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell. United States. 12 (12): 3839–51. doi:10.1091/mbc.12.12.3839. ISSN 1059-1524. PMC 60759. PMID 11739784.
  8. Ohta, T; Michel J J; Schottelius A J; Xiong Y (Apr 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol. Cell. UNITED STATES. 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. ISSN 1097-2765. PMID 10230407.
  9. Vodermaier, Hartmut C; Gieffers, Christian; Maurer-Stroh, Sebastian; Eisenhaber, Frank; Peters, Jan-Michael (Sep 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. England. 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. ISSN 0960-9822. PMID 12956947. S2CID 5942532.

Further reading

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