APOL6

Apolipoprotein L6 is a protein that in humans is encoded by the APOL6 gene.[5][6][7]

APOL6
Identifiers
AliasesAPOL6, APOL-VI, APOLVI, apolipoprotein L6
External IDsOMIM: 607256 MGI: 1919189 HomoloGene: 49940 GeneCards: APOL6
Gene location (Human)
Chr.Chromosome 22 (human)[1]
Band22q12.3Start35,648,446 bp[1]
End35,668,404 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

80830

71939

Ensembl

ENSG00000221963

ENSMUSG00000033576

UniProt

Q9BWW8

n/a

RefSeq (mRNA)

NM_030641

NM_001163621
NM_028010

RefSeq (protein)

NP_085144

n/a

Location (UCSC)Chr 22: 35.65 – 35.67 MbChr 15: 77.04 – 77.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000221963 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000033576 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". Genomics. 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903.
  6. Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells". Mol Cancer Res. 3 (1): 21–31. PMID 15671246.
  7. "Entrez Gene: APOL6 apolipoprotein L, 6".

Further reading


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