ARHGAP27

ARHGAP27
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3PP2
Identifiers
Aliases	ARHGAP27, CAMGAP1, PP905, SH3D20, SH3P20, Rho GTPase activating protein 27
External IDs	OMIM: 610591 MGI: 1916903 HomoloGene: 45715 GeneCards: ARHGAP27
Gene location (Human)
Chr.	Chromosome 17 (human)[1]
End	45,434,421 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	103,363,692 bp[2]
Gene ontology
Molecular function	• SH3 domain binding; • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity;
Cellular component	• intracellular; • membrane; • cell nucleus; • nucleoplasm; • cytoplasm; • cytosol;
Biological process	• endocytosis; • signal transduction; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • receptor-mediated endocytosis; • GO:0043087, GO:0032313, GO:0032319, GO:0032314, GO:0043088 regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	201176
	544817
	ENSG00000159314; ENSG00000276836; ENSG00000276907
	ENSMUSG00000034255
	Q6ZUM4; Q8N2Y9
	A2AB59
	NM_001159330; NM_001282290; NM_174919; NM_199282
	NM_001205236; NM_133715; NM_183288
	NP_001269219; NP_777579; NP_954976; NP_954976.1
	NP_001192165; NP_598476; NP_899111
	Wikidata
View/Edit Human	View/Edit Mouse

Rho GTPase activating protein 27 is a protein that in humans is encoded by the ARHGAP27 gene. [5]

Function

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may play a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013].

References

ENSG00000276836, ENSG00000276907 GRCh38: Ensembl release 89: ENSG00000159314, ENSG00000276836, ENSG00000276907 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000034255 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Rho GTPase activating protein 27". Retrieved 2018-05-30.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Rho GTPase-activating protein 27 (ARHGAP27)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] ENSG00000276836, ENSG00000276907 GRCh38: Ensembl release 89: ENSG00000159314, ENSG00000276836, ENSG00000276907 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034255 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Rho GTPase activating protein 27". Retrieved 2018-05-30.