ASB1

Ankyrin repeat and SOCS box protein 1 is a protein that is in humans, encoded by the ASB1 gene.[5]

ASB1
Identifiers
AliasesASB1, ASB-1, ankyrin repeat and SOCS box containing 1
External IDsOMIM: 605758 MGI: 1929735 HomoloGene: 9390 GeneCards: ASB1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2q37.3Start238,426,742 bp[1]
End238,452,250 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

51665

65247

Ensembl

ENSG00000065802

ENSMUSG00000026311

UniProt

Q9Y576

Q9WV74

RefSeq (mRNA)

NM_001040445
NM_016114
NM_001330196

NM_001039126
NM_023046

RefSeq (protein)

NP_001035535
NP_001317125

NP_001034215
NP_075533

Location (UCSC)Chr 2: 238.43 – 238.45 MbChr 1: 91.54 – 91.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000065802 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026311 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: ASB1 ankyrin repeat and SOCS box-containing 1".

Further reading


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