ASB13

Ankyrin repeat and SOCS box protein 13 is a protein that in humans is encoded by the ASB13 gene.[4][5]

ASB13
Identifiers
AliasesASB13, ankyrin repeat and SOCS box containing 13
External IDsOMIM: 615055 MGI: 2145525 HomoloGene: 11666 GeneCards: ASB13
Gene location (Human)
Chr.Chromosome 10 (human)[1]
Band10p15.1Start5,638,867 bp[1]
End5,666,595 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

79754

142688

Ensembl

ENSG00000196372

ENSMUSG00000033781

UniProt

Q8WXK3

Q8VBX0

RefSeq (mRNA)

NM_024701

NM_001267724
NM_178283

RefSeq (protein)

NP_078977

NP_001254653
NP_840068

Location (UCSC)Chr 10: 5.64 – 5.67 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length sequences are not known.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000196372 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM, Hilton DJ (Jun 2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem Sci. 27 (5): 235–41. doi:10.1016/S0968-0004(02)02085-6. PMID 12076535.
  5. "Entrez Gene: ASB13 ankyrin repeat and SOCS box-containing 13".

Further reading


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