ASTEROID trial

The ASTEROID trial was a clinical trial published in 2006 that shows the effects of statins (drugs that inhibit the enzyme HMG-CoA reductase) on atherosclerosis. Employing intravascular ultrasound (IVUS), they showed regression of the atherosclerotic plaques in response to a high dose of rosuvastatin[1]

References

Nissen SE, Nicholls SJ, Sipahi I, Libby P, Raichlen JS, Ballantyne CM, Davignon J, Erbel R, Fruchart JC, Tardif JC, Schoenhagen P, Crowe T, Cain V, Wolski K, Goormastic M, Tuzcu EM; ASTEROID Investigators. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006;295:1556-65. doi:10.1001/jama.295.13.jpc60002 PMID 16533939.

External links

clinicaltrials.gov entry

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