Acetophenone carboxylase
Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction
- 2 ATP + acetophenone + HCO3− + H2O + H+ 2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate
| Acetophenone carboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 6.4.1.8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme is involved in anaerobic degradation of ethylbenzene.
References
- Jobst B, Schühle K, Linne U, Heider J (March 2010). "ATP-dependent carboxylation of acetophenone by a novel type of carboxylase". Journal of Bacteriology. 192 (5): 1387–94. doi:10.1128/jb.01423-09. PMC 2820866. PMID 20047908.
External links
- Acetophenone+carboxylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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