Alan Grossman

Alan D. Grossman, is an American microbiologist who is currently the head of the Department of Biology at the Massachusetts Institute of Technology. In 2014, he was elected to the National Academy of Sciences.[1]

Career

Initially, his research was focused on characterization of bacterial chromosome segregation. His group was among the first that identified the Spo0J protein, the homologue of ParB, responsible for the process of chromosome segregation in B. subtilis.[2] He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ParS.[3]

References
  1. http://www.nasonline.org/member-directory/members/20033164.html
  2. Ireton K, Gunther NW, Grossman AD (1994). "spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis". J Bacteriol. 176 (17): 5320–9. doi:10.1128/jb.176.17.5320-5329.1994. PMC 196717. PMID 8071208.CS1 maint: multiple names: authors list (link)
  3. Lin DC, Grossman AD (1998). "Identification and characterization of a bacterial chromosome partitioning site". Cell. 92 (5): 675–85. doi:10.1016/s0092-8674(00)81135-6. hdl:1721.1/83851. PMID 9506522.


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