Alcohol-forming fatty acyl-CoA reductase

Alcohol-forming fatty acyl-CoA reductase (EC 1.2.1.84, FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase.[1] This enzyme catalyses the following chemical reaction

a long-chain acyl-CoA + 2 NADPH + 2 H+ a long-chain alcohol + 2 NADP+ + coenzyme A
Alcohol-forming fatty acyl-CoA reductase
Identifiers
EC number1.2.1.84
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme has been characterized from the plant Simmondsia chinensis.

References

  1. Metz JG, Pollard MR, Anderson L, Hayes TR, Lassner MW (March 2000). "Purification of a jojoba embryo fatty acyl-coenzyme A reductase and expression of its cDNA in high erucic acid rapeseed". Plant Physiology. 122 (3): 635–44. doi:10.1104/pp.122.3.635. PMC 58898. PMID 10712526.
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