Aminomethyl group

In organic chemistry, an aminomethyl group is a monovalent functional group with formula −CH
2−NH
2 or −CH
4N. It can be described as a methylene bridge −CH
2− with one bond filled by an amino group −NH
2.

It is one of a series of 1-aminoalkyl groups of the form −(CH
2−)
nNH
2.[1]

Aminomethyl is used in the standard (IUPAC) names of some compounds,[2] such as 4-(aminomethyl) benzoic acid.

References
  1. Erwin Von Angerer, Norbert Knebel, Mario Kager, and Bernhard Ganss (1990): "1-(aminoalkyl)-2-phenylindoles as novel pure estrogen antagonists". Journal of Medicinal Chemistry, volume 33, issue 9, pages 2635–2640. doi:10.1021/jm00171a045
  2. Ursula Bünzli-Trepp (2007): Systematic Nomenclature of Organic, Organometallic and Coordination Chemistry: Chemical-Abstracts Guidelines with IUPAC Recommendations and Many Trivial Names. EPFL Press, 636 pages. ISBN 9781420046151


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