CACTIN

CACTIN
Identifiers
Aliases	CACTIN, C19orf29, NY-REN-24, fSAPc, cactin, spliceosome C complex subunit
External IDs	OMIM: 618536 MGI: 1917562 HomoloGene: 69553 GeneCards: CACTIN
Gene location (Human)
Chr.	Chromosome 19 (human)[1]
End	3,626,815 bp[1]
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)[2]
End	81,326,242 bp[2]
Gene ontology
Molecular function	• GO:0001948 protein binding; • RNA binding;
Cellular component	• catalytic step 2 spliceosome; • nucleoplasm; • spliceosomal complex; • extracellular exosome; • cell nucleus; • cytosol; • nuclear speck; • cytoplasm;
Biological process	• negative regulation of protein phosphorylation; • mRNA splicing, via spliceosome; • immune system process; • negative regulation of type I interferon-mediated signaling pathway; • cellular response to tumor necrosis factor; • mRNA processing; • negative regulation of interferon-beta production; • negative regulation of lipopolysaccharide-mediated signaling pathway; • multicellular organism development; • negative regulation of interleukin-8 production; • negative regulation of toll-like receptor signaling pathway; • cellular response to interleukin-1; • RNA splicing; • negative regulation of tumor necrosis factor production; • innate immune system; • cellular response to lipopolysaccharide; • negative regulation of NF-kappaB transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	58509
	70312
	ENSG00000105298
	ENSMUSG00000034889
	Q8WUQ7
	Q9CS00
	NM_001080543; NM_021231
	NM_027381
	NP_001074012; NP_067054
	NP_081657
	Wikidata
View/Edit Human	View/Edit Mouse

Cactin also known as renal carcinoma antigen NY-REN-24 is a protein that in humans is encoded by the CACTIN gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000105298 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000034889 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
"Entrez Gene: C19orf29 chromosome 19 open reading frame 29".

Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. doi:10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5. PMID 10508479.
Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC 1370266. PMID 11991638.
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Sogayar MC, Camargo AA, Bettoni F, et al. (2004). "A transcript finishing initiative for closing gaps in the human transcriptome". Genome Res. 14 (7): 1413–23. doi:10.1101/gr.2111304. PMC 442158. PMID 15197164.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105298 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034889 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8619474-5] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

[pmid9110174-6] Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.

[entrez-7] "Entrez Gene: C19orf29 chromosome 19 open reading frame 29".

CACTIN

References

Further reading