CCNB1IP1

E3 ubiquitin-protein ligase CCNB1IP1 is an enzyme that in humans is encoded by the CCNB1IP1 gene.[5][6]

CCNB1IP1
Identifiers
AliasesCCNB1IP1, C14orf18, HEI10, cyclin B1 interacting protein 1
External IDsOMIM: 608249 MGI: 2685134 HomoloGene: 18819 GeneCards: CCNB1IP1
Gene location (Human)
Chr.Chromosome 14 (human)[1]
Band14q11.2Start20,311,368 bp[1]
End20,333,312 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

57820

239083

Ensembl

ENSG00000100814

ENSMUSG00000071470

UniProt

Q9NPC3

D3Z3K2

RefSeq (mRNA)

NM_182852
NM_021178
NM_182849
NM_182851

NM_001111119

RefSeq (protein)

NP_067001
NP_878269
NP_878272

NP_001104589

Location (UCSC)Chr 14: 20.31 – 20.33 MbChr 14: 50.79 – 50.81 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM][6] It is considered a housekeeping gene.

References

  1. GRCh38: Ensembl release 89: ENSG00000100814 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000071470 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Toby GG, Gherraby W, Coleman TR, Golemis EA (Mar 2003). "A Novel RING Finger Protein, Human Enhancer of Invasion 10, Alters Mitotic Progression through Regulation of Cyclin B Levels". Mol Cell Biol. 23 (6): 2109–2122. doi:10.1128/MCB.23.6.2109-2122.2003. PMC 149478. PMID 12612082.
  6. "Entrez Gene: CCNB1IP1 cyclin B1 interacting protein 1".

Further reading

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.