CENTG1

Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the AGAP2 gene.[5]

AGAP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesAGAP2, CENTG1, GGAP2, PIKE, ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
External IDsOMIM: 605476 MGI: 3580016 HomoloGene: 86815 GeneCards: AGAP2
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q14.1Start57,723,761 bp[1]
End57,742,157 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

116986

216439

Ensembl

ENSG00000135439

ENSMUSG00000025422

UniProt

Q99490

Q3UHD9

RefSeq (mRNA)

NM_001122772
NM_014770

NM_001033263
NM_001301014

RefSeq (protein)

NP_001116244
NP_055585

NP_001028435
NP_001287943

Location (UCSC)Chr 12: 57.72 – 57.74 MbChr 10: 127.08 – 127.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

CENTG1 has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000135439 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025422 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: CENTG1 centaurin, gamma 1".
  6. Ye K, Hurt KJ, Wu FY, Fang M, Luo HR, Hong JJ, Blackshaw S, Ferris CD, Snyder SH (December 2000). "Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N". Cell. 103 (6): 919–30. doi:10.1016/S0092-8674(00)00195-1. PMID 11136977. S2CID 16610638.
  7. Rong R, Ahn JY, Huang H, Nagata E, Kalman D, Kapp JA, Tu J, Worley PF, Snyder SH, Ye K (November 2003). "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis". Nat. Neurosci. 6 (11): 1153–61. doi:10.1038/nn1134. PMID 14528310. S2CID 807407.

Further reading


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