CKS2

Cyclin-dependent kinases regulatory subunit 2 is a protein that in humans is encoded by the CKS2 gene.[5][6][7]

CKS2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCKS2, CKSHS2, CDC28 protein kinase regulatory subunit 2
External IDsOMIM: 116901 MGI: 1913447 HomoloGene: 86883 GeneCards: CKS2
Gene location (Human)
Chr.Chromosome 9 (human)[1]
Band9q22.2Start89,311,195 bp[1]
End89,316,703 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

1164

66197

Ensembl

ENSG00000123975

ENSMUSG00000062248

UniProt

P33552

P56390

RefSeq (mRNA)

NM_001827

NM_025415

RefSeq (protein)

NP_001818

NP_079691

Location (UCSC)Chr 9: 89.31 – 89.32 MbChr 13: 51.65 – 51.65 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000123975 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000062248 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Richardson HE, Stueland CS, Thomas J, Russell P, Reed SI (Dec 1990). "Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe". Genes Dev. 4 (8): 1332–44. doi:10.1101/gad.4.8.1332. PMID 2227411.
  6. Demetrick DJ, Zhang H, Beach DH (Sep 1996). "Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22". Cytogenet Cell Genet. 73 (3): 250–4. doi:10.1159/000134349. PMID 8697818.
  7. "Entrez Gene: CKS2 CDC28 protein kinase regulatory subunit 2".

Further reading


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