CPNE4

Copine-4 is a protein that in humans is encoded by the CPNE4 gene.[5][6][7]

CPNE4
Identifiers
AliasesCPNE4, COPN4, CPN4, copine 4
External IDsOMIM: 604208 MGI: 1921270 HomoloGene: 26078 GeneCards: CPNE4
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q22.1Start131,533,555 bp[1]
End132,285,410 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

131034

74020

Ensembl

ENSG00000196353

ENSMUSG00000032564

UniProt

Q96A23
Q4G168

Q8BLR2

RefSeq (mRNA)

NM_001289112
NM_130808
NM_153429

NM_028719
NM_001357439
NM_001378996

RefSeq (protein)

NP_082995
NP_001344368
NP_001365925

Location (UCSC)Chr 3: 131.53 – 132.29 MbChr 9: 104.55 – 105.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm.

This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000196353 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000032564 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Creutz CE, Tomsig JL, Snyder SL, Gautier MC, Skouri F, Beisson J, Cohen J (Feb 1998). "The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans". J Biol Chem. 273 (3): 1393–402. doi:10.1074/jbc.273.3.1393. PMID 9430674.
  6. Maitra R, Grigoryev DN, Bera TK, Pastan IH, Lee B (Apr 2003). "Cloning, molecular characterization, and expression analysis of Copine 8". Biochem Biophys Res Commun. 303 (3): 842–7. doi:10.1016/S0006-291X(03)00445-5. PMID 12670487.
  7. "Entrez Gene: CPNE4 copine IV".

Further reading


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