Clostridial vaccine
A clostridial vaccine is a vaccine for sheep and cattle that protects against diseases caused by toxins produced by an infection with one or more Clostridium bacteria.[1] Clostridial vaccines are often administered to pregnant ewes a few weeks before they are due to give birth, in order to give passive immunity to their lambs.[1] Clostridial bacteria multiply rapidly in infected sheep, and produce large amounts of toxin which can cause the sheep to die within hours.[2]
Clostridial vaccines can contain anti-toxins to one or more endotoxins produced by the following bacteria:[1]
- Clostridium chauvoei
- Clostridium haemolyticum
- Clostridium novyi
- Clostridium perfringens
- Clostridium septicum
- Clostridium sordellii
- Clostridium tetani
Clostridial vaccines which protect sheep against multiple clostridial diseases have been available since the 1950s.[3]
References
- Duncanson, Graham R. (2012). "Vaccines for sheep. Clostridial diseases". Veterinary Treatment of Sheep and Goats. CABI. p. 97. ISBN 9781780640051.
- Scott, Phillip R. (2006). "Clostridial diseases". Sheep Medicine. CRC Press. p. 125. ISBN 9781840765366.
- Sargison, Neil (2009). Sheep flock health: a planned approach. John Wiley & Sons. p. 263. ISBN 9781444302608.
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