CorA metal ion transporter

The CorA transport system is the primary Mg2+ influx system of Salmonella typhimurium and Escherichia coli.[2][3] CorA is ubiquitous in the Bacteria and Archaea. There are also eukaryotic members of the family localized to the mitochondrial membrane such as MRS2 and Lpe10 in yeast.

CorA-like Mg2+ transporter protein
Structure of the CorA Mg2+ transporter.[1]
Identifiers
SymbolCorA
PfamPF01544
InterProIPR002523
TCDB1.A.35
OPM superfamily66
OPM protein2bbj
CDDcd11744

Subfamilies

Human proteins containing this domain

MRS2L;

References

  1. Lunin VV, Dobrovetsky E, Khutoreskaya G, et al. (April 2006). "Crystal structure of the CorA Mg2+ transporter". Nature. 440 (7085): 833–7. Bibcode:2006Natur.440..833L. doi:10.1038/nature04642. PMC 3836678. PMID 16598263.
  2. Maguire ME, Kehres DG, Lawyer CH (1998). "The CorA magnesium transporter gene family". Microb. Comp. Genom. 3 (3): 151–169. doi:10.1089/omi.1.1998.3.151. PMID 9775386.
  3. Smith RL, Maguire ME, Szegedy MA, Kucharski LM, Walker C, Wiet RM, Redpath A, Kaczmarek MT (1998). "The CorA Mg2+ transport protein of Salmonella typhimurium. Mutagenesis of conserved residues in the third membrane domain identifies a Mg2+ pore". J. Biol. Chem. 273 (44): 28663–28669. doi:10.1074/jbc.273.44.28663. PMID 9786860.

Further reading

This article incorporates text from the public domain Pfam and InterPro: IPR002523


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