Cynthia Larive

Larive received her bachelor of science from South Dakota State University in 1980, and her Masters of Science degree from Purdue University in 1982. In 1992, she was awarded a Ph.D. in Chemistry from the University of California, Riverside after working under the direction of Dallas L. Rabenstein.[1][2][3]

Larive began her career as a professor in the chemistry department at the University of Kansas, and later joined the faculty of the University of California, Riverside, in 2005.[2] Since 2004 she has served as the editor-in-chief of the Analytical Sciences Digital Library.[4]

In February 2017, Larive was appointed interim provost and executive vice chancellor for University of California, Riverside, and the appointment was made permanent in October.[5]

On May 16, 2019, Larive was announced as the new Chancellor of University of California, Santa Cruz, succeeding George Blumenthal[6] effective July 1.[7]

Larive worked in the field of bioanalytical chemistry, applying analytical tools such as nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry to the products of chemical separations. Much of her research focused on reducing the amount of sample needed for analysis, such as constructing microcoil NMR probes that can measure as little as 25 nL of sample and are usable as part of an capillary isotachophoresis apparatus. This has been applied to structure determination of heparin and heparan sulfate.[1][8] She developed NMR pulse sequences to study protein ligand interactions in complexes with multiple ligands.[1][9] She also researches analytical methods for metabolomics[1][10] and chemogenomics for the reaction of plants to pesticides and hypoxia using NMR and mass spectroscopy.[1]

NMR is often thought of as a low-sensitivity method, but Larive's laboratory has developed ways of increasing the sensitivity of their measurements to obtain precise chemical and structural information.[11] The techniques she has developed are relevant to understanding carbohydrate structure and biosynthesis, designing new drugs and measuring the purity of pharmaceuticals.[12] Her work in developing chemical profiles for substances also has relevance for the authentication of foodstuffs such as wine, olive oil, and pomegranate juice.[13]

Larive has received a number of awards, including the National Science Foundation CAREER Award in 1995.[14] She received the American Chemical Society Analytical Division's J. Calvin Giddings Award for Excellence in Education in 2007[15] and served as chair of the Analytical Division in 2013. In 2015, Larive received the Award for Volunteer Service to the American Chemical Society.[4] In 2018, the Analytical Chemistry Division of the American Chemical Society honored Larive with the Award for Distinguished Service to the Field of Analytical Chemistry.

Larive is a Fellow of the American Association for the Advancement of Science (AAAS) (2008),[16] the International Union of Pure and Applied Chemistry (IUPAC) (2004) and the American Chemical Society (ACS) (2011).[17]