DBF4

Protein DBF4 homolog A is a protein that is encoded by the DBF4 gene in humans.[5][6][7]

DBF4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDBF4, ASK, CHIF, DBF4A, ZDBF1, DBF4 zinc finger
External IDsOMIM: 604281 MGI: 1351328 HomoloGene: 40892 GeneCards: DBF4
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q21.12Start87,876,216 bp[1]
End87,909,553 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

10926

27214

Ensembl

ENSG00000006634

ENSMUSG00000002297

UniProt

Q9UBU7

Q9QZ41

RefSeq (mRNA)

NM_006716
NM_001318060
NM_001318061
NM_001318062

NM_001190717
NM_013726

RefSeq (protein)

NP_001304989
NP_001304990
NP_001304991
NP_006707

NP_001177646
NP_038754

Location (UCSC)Chr 7: 87.88 – 87.91 MbChr 5: 8.4 – 8.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

DBF4 has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000006634 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000002297 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H (Jul 1999). "A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells". Molecular and Cellular Biology. 19 (7): 5083–95. doi:10.1128/MCB.19.7.5083. PMC 84351. PMID 10373557.
  6. Lepke M, Pütter V, Staib C, Kneissl M, Berger C, Hoehn K, Nanda I, Schmid M, Grummt F (Sep 1999). "Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes". Molecular & General Genetics. 262 (2): 220–9. doi:10.1007/s004380051078. PMID 10517317. S2CID 24878962.
  7. "Entrez Gene: DBF4 DBF4 homolog (S. cerevisiae)".
  8. Kneissl M, Pütter V, Szalay AA, Grummt F (Mar 2003). "Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells". Journal of Molecular Biology. 327 (1): 111–28. doi:10.1016/s0022-2836(03)00079-2. PMID 12614612.
  9. Jiang W, McDonald D, Hope TJ, Hunter T (Oct 1999). "Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication". The EMBO Journal. 18 (20): 5703–13. doi:10.1093/emboj/18.20.5703. PMC 1171637. PMID 10523313.

Further reading


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