DKK4

DKK4
Identifiers
Aliases	DKK4, DKK-4, dickkopf WNT signaling pathway inhibitor 4
External IDs	OMIM: 605417 MGI: 2385299 HomoloGene: 8680 GeneCards: DKK4
Gene location (Human)
Chr.	Chromosome 8 (human)[1]
End	42,377,229 bp[1]
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)[2]
End	22,627,547 bp[2]
Gene ontology
Molecular function	• molecular function; • co-receptor binding; • receptor antagonist activity;
Cellular component	• extracellular region; • cellular component; • extracellular;
Biological process	• multicellular organism development; • negative regulation of Wnt signaling pathway; • Wnt signaling pathway; • negative regulation of canonical Wnt signaling pathway; • negative regulation of hair follicle placode formation; • extracellular negative regulation of signal transduction; • negative regulation of receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	27121
	234130
	ENSG00000104371
	ENSMUSG00000031535
	Q9UBT3
	Q8VEJ3
	NM_014420
	NM_145592
	NP_055235
	NP_663567
	Wikidata
View/Edit Human	View/Edit Mouse

Dickkopf-related protein 4 is a protein in the Dickkopf family that in humans is encoded by the DKK4 gene.[5]

References

GRCh38: Ensembl release 89: ENSG00000104371 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000031535 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, et al. (October 1999). "Functional and structural diversity of the human Dickkopf gene family". Gene. 238 (2): 301–13. doi:10.1016/S0378-1119(99)00365-0. PMID 10570958.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.