DPYSL5

Dihydropyrimidinase-related protein 5 is an enzyme that in humans is encoded by the DPYSL5 gene.[5][6][7]

DPYSL5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDPYSL5, CRAM, CRMP-5, CRMP5, Ulip6, dihydropyrimidinase like 5, CV2
External IDsOMIM: 608383 MGI: 1929772 HomoloGene: 41347 GeneCards: DPYSL5
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p23.3Start26,847,747 bp[1]
End26,950,351 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

56896

65254

Ensembl

ENSG00000157851

ENSMUSG00000029168

UniProt

Q9BPU6

Q9EQF6

RefSeq (mRNA)

NM_020134
NM_001253723
NM_001253724

NM_023047
NM_001356948
NM_001356949

RefSeq (protein)

NP_001240652
NP_001240653
NP_064519

NP_075534
NP_001343877
NP_001343878

Location (UCSC)Chr 2: 26.85 – 26.95 MbChr 5: 30.71 – 30.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.[supplied by OMIM][7]

References

  1. GRCh38: Ensembl release 89: ENSG00000157851 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000029168 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Inatome R, Tsujimura T, Hitomi T, Mitsui N, Hermann P, Kuroda S, Yamamura H, Yanagi S (Oct 2000). "Identification of CRAM, a novel unc-33 gene family protein that associates with CRMP3 and protein-tyrosine kinase(s) in the developing rat brain". J Biol Chem. 275 (35): 27291–302. doi:10.1074/jbc.M910126199. PMID 10851247.
  6. Horiuchi M, El Far O, Betz H (Nov 2000). "Ulip6, a novel unc-33 and dihydropyrimidinase related protein highly expressed in developing rat brain". FEBS Lett. 480 (2–3): 283–6. doi:10.1016/S0014-5793(00)01952-9. PMID 11034345. S2CID 42248702.
  7. "Entrez Gene: DPYSL5 dihydropyrimidinase-like 5".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q9BPU6 (Dihydropyrimidinase-related protein 5) at the PDBe-KB.
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