DYNLT1

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[4][5][6]

DYNLT1
Identifiers
AliasesDYNLT1, CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1
External IDsOMIM: 601554 MGI: 98643 HomoloGene: 4754 GeneCards: DYNLT1
Gene location (Human)
Chr.Chromosome 6 (human)[1]
Band6q25.3Start158,636,474 bp[1]
End158,644,743 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

6993

21648

Ensembl

ENSG00000146425

n/a

UniProt

P63172

P51807

RefSeq (mRNA)

NM_006519
NM_001291602
NM_001291603

NM_009342

RefSeq (protein)

NP_001278531
NP_001278532
NP_006510

NP_001160102
NP_001160099
NP_001186877
NP_001160101
NP_033368

Location (UCSC)Chr 6: 158.64 – 158.64 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][6]

References

  1. GRCh38: Ensembl release 89: ENSG00000146425 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet. 73 (1–2): 153–6. doi:10.1159/000134329. PMID 8646886.
  5. Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502.
  6. "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1".

Further reading


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