Daphnoretin
Daphnoretin is a protein kinase C activator isolated from Wikstroemia indica C.A. Mey, one of the 50 fundamental herbs in traditional Chinese medicine.[1][2] It has also been found to occur in Stellera chamaejasme - the single species in a genus closely related to Wikstroemia within the family Thymelaceae.[3]
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IUPAC name
7-Hydroxy-6-methoxy-3-(2-oxochromen-7-yl)oxychromen-2-one | |
Other names
Thymelol | |
Identifiers | |
3D model (JSmol) |
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CompTox Dashboard (EPA) |
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Properties | |
C19H12O7 | |
Molar mass | 352.298 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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References
- Gu, Shoubin; He, Jinhai (January 9, 1012). "Daphnoretin induces cell cycle arrest and apoptosis in human osteosarcoma (HOS) cells". Molecules. MDPI. 17 (1): 598–612. doi:10.3390/molecules17010598. PMC 6268824. PMID 22231496.
- Ko, Feng N.; Chang, Ya L.; Kuo, Yueh H.; Lin, Yun L.; Teng, Che M. (October 1, 1993). "Daphnoretin, a new protein kinase C activator isolated from Wikstroemia indica C.A. Mey". Biochemical Journal. Portland Press Limited. 295 (1): 321–327. doi:10.1042/bj2950321. PMC 1134857. PMID 8216237.
- Medicinal Plants in Mongolia pub. World Health Organization, Regional Office for the Western Pacific Region 2013 ISBN 978 92 9061 632 0 http://www.wpro.who.int/publications/Medicinal_Plants_in_Mongolia_VF.pdf
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