Demetrius Klee Lopes

Demetrius Klee Lopes (born March 19, 1970) is a cerebrovascular neurosurgeon specializing in neuroendovascular therapy. At Advocate Health, he serves as medical director of the cerebrovascular and neuroendovascular program and is co-director of their stroke program.[3]

Demetrius Klee Lopes
Born (1970-03-19) March 19, 1970
Chicago[1]
NationalityAmerican
EducationFederal University of Rio Grande do Sul (1993), State University of New York at Buffalo (1995)
OccupationNeurosurgeon
Years active1994 – present
Known forNeuroendovascular surgery[2]
Children2[1]
Websitewww.demetriuslopesmd.com

Lopes is a guest faculty member of Brigham and Women's Hospital Cerebrovascular and Skull Base Symposium at Harvard Medical School.[4] Lopes is the founder of nonprofit Cure4Stroke Foundation,[5] editor in chief of "Neurovascular Exchange" educational website[2] and serves on the organizing committee of the annual World Live Neurovascular Conference.[6]

Lopes' contributions to neurovascular surgery have improved safety and decreased the disabilities caused by stroke, brain aneurysms and arterial malformations. He collaborated on major studies that defined the current indications for mechanical thrombectomy for the treatment of acute stroke. In addition, Lopes had contributed significantly to the development of flow diversion treatment for cerebral aneurysms.[7]

Early life and education

Born on March 19, 1970, Lopes lived in Brazil until 1993.[1] He began his medical education in 1987 at Federal University of Rio Grande do Sul. After completing his doctorate in medicine in 1993, he completed his residency and fellowship at State University of New York at Buffalo.[2]

Career

In 2001, Lopes joined Rush University Medical Center.[2] In May 2006, he was voted Chicago's "Dr. McDreamy" by the readers of the Chicago Tribune.[1]

In 2013, Lopes founded the nonprofit Cure4Stroke Foundation,[8][5] which aims to raise stroke awareness and celebrate stroke survivors.[9]

In 2015, Lopes published articles confirming that the use of endovascular therapy for ischemic stroke improves patient outcomes.[10][11][12]

In 2015, along with Elad Levy, Lopes performed research resulting in paradigm shifts in the treatment of cerebrovascular diseases, including being the US Interventional Principal Investigator for the SWIFT PRIME trials.[13] Lopes also conducted research on the efficacy and safety of endovascular thrombectomy in 2018.[14]

In July 2018, Lopes joined Advocate Health Care as co-director of the stroke program.[3]

In 2019, Lopes published a preliminary study on usage of the pipeline embolization device to treat small to medium-sized intracranial aneurysms,[7] and has also demonstrated its safety and efficacy for patients under 22 years old.[15] Later that year, Lopes also published research results demonstrating the safety and efficacy of transvenous embolization for treating arteriovenous malformations.[16] Lopes published another similar study in July 2020.[17]

Selected publications
  • Saver, JL; Goyal, M; Bonafe, A; Diener, HC; Levy, EI; Pereira, VM; Albers, GW; Cognard, C; Cohen, DJ; Hacke, W; Jansen, O; Jovin, TG; Mattle, HP; Nogueira, RG; Siddiqui, AH; Yavagal, DR; Baxter, BW; Devlin, TG; Lopes, DK; Reddy, VK; de Rochemont, R; Singer, OC; Jahan, R (2015). "Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke" (PDF). N Engl J Med. 372 (24): 2285–95. doi:10.1056/NEJMoa1415061. PMID 25882376.
  • Kerolus, MG; Tan, LA; Lopes, DK (2017). "Giant vein of Galen malformation in an adult". Radiol Case Rep. 12 (3): 585–589. doi:10.1016/j.radcr.2017.03.012. PMC 5551915. PMID 28828131.
  • Spiotta, AM; Derdeyn, CP; Tateshima, S; Mocco, J; Crowley, RW; Liu, KC; Jensen, L; Ebersole, K; Reeves, A; Lopes, DK; Hanel, RA; Sauvageau, E; Duckwiler, G; Siddiqui, A; Levy, E; Puri, A; Pride, L; Novakovic, R; Chaudry, MI; Turner, RD; Turk, AS (2017). "Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms". Neurosurgery. 81: 56–65. doi:10.1093/neuros/nyx085. PMID 28449126. S2CID 3806248.
  • Yoo, AJ; Khatri, P; Mocco, J; Zaidat, OO; Gupta, R; Frei, D; Lopes, D; Shownkeen, H; Berkhemer, OA; Meyer, D; Hak, SS; Kuo, SS; Buell, H; Bose, A; Sit, SP; von Kummer, R (2017). "Impact of Thrombus Length on Outcomes After Intra-Arterial Aspiration Thrombectomy in the THERAPY Trial". Stroke. 48 (7): 1895–1900. doi:10.1161/STROKEAHA.116.016253. PMID 28596447. S2CID 279737.
  • Nogueira, RG; Jadhav, AP; Haussen, DC; Bonafe, A; Budzik, RF; Bhuva, P; Yavagal, DR; Ribo, M; Cognard, C; Hanel, RA; Sila, CA; Hassan, AE; Millan, M; Levy, EI; Mitchell, P; Chen, M; English, JD; Shah, QA; Silver, FL; Pereira, VM; Mehta, BP; Baxter, BW; Abraham, MG; Cardona, P; Veznedaroglu, E; Hellinger, FR; Feng, L; Kirmani, JF; Lopes, DK; Jankowitz, BT; Frankel, MR; Costalat, V; Vora, NA; Yoo, AJ; Malik, AM; Furlan, AJ; Rubiera, M; Aghaebrahim, A; Olivot, JM; Tekle, WG; Shields, R; Graves, T; Lewis, RJ; Smith, WS; Liebeskind, DS; Saver, JL; Jovin, TG (2018). "Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct". N Engl J Med. 378: 11–21. doi:10.1056/NEJMoa1706442. PMID 29129157.

References
  1. Beth Sammon (2006-05-21). "You will see Dr. McDreamy now". Chicago Tribune. Archived from the original on 2017-08-16. Retrieved 2017-11-08.
  2. "Demetrius K. Lopes, MD". Rush University. Archived from the original on 2017-03-19. Retrieved 2017-11-08.
  3. Mackenzie Garrity (2018-07-31). "Neurosurgeon joins Advocate Brain & Spine Institute as director of cerebrovascular program: 5 takeaways". The Becker's Spine Review. Archived from the original on 2018-08-01. Retrieved 2018-08-01.
  4. "Brigham and Women's Hospital Cerebrovascular and Skull Base Symposium: Faculty". Harvard Medical School. Archived from the original on 2017-09-26. Retrieved 2017-11-08.
  5. "Mission and Board of Directors". www.cure4stroke.org. Archived from the original on 2017-09-06. Retrieved 2017-11-08.
  6. Group), Milk Creative & Events (by DEKON. "COMMITTEES". www.wlnc.org. Retrieved 20 August 2017.
  7. Hanel RA, Kallmes DF, Lopes DK, Nelson PK, Siddiqui A, Jabbour P, Pereira VM, Szikora István I, Zaidat OO, Bettegowda C, Colby GP, Mokin M, Schirmer C, Hellinger FR, Given Ii C, Krings T, Taussky P, Toth G, Fraser JF, Chen M, Priest R, Kan P, Fiorella D, Frei D, Aagaard-Kienitz B, Diaz O, Malek AM, Cawley CM, Puri AS (July 2019). "Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results". J Neurointerv Surg. 12 (1): 62–66. doi:10.1136/neurintsurg-2019-015091. PMC 6996098. PMID 31308197.
  8. "cure4stroke.org". donatecube.com. Archived from the original on 2017-11-08. Retrieved 2017-11-08.
  9. "Cure4Stroke Foundation Presents "MOVE that BODY!" Main Event: 5k Fun Run/Walk, Zumba, and Yin Yoga". active.com. 2015-07-07. Archived from the original on 2017-11-08. Retrieved 2017-11-08.
  10. Saver, Jeffrey L.; Goyal, Mayank; Bonafe, Alain; Diener, Hans-Christoph; Levy, Elad I.; Pereira, Vitor M.; Albers, Gregory W.; Cognard, Christophe; Cohen, David J.; Hacke, Werner; Jansen, Olav; Jovin, Tudor G.; Mattle, Heinrich P.; Nogueira, Raul G.; Siddiqui, Adnan H.; Yavagal, Dileep R.; Baxter, Blaise W.; Devlin, Thomas G.; Lopes, Demetrius K.; Reddy, Vivek K.; et al. (June 2015). "Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke" (PDF). New England Journal of Medicine. 372 (24): 2285–2295. doi:10.1056/NEJMoa1415061. PMID 25882376.
  11. Lecia Bushak (2015-04-17). "New Approach To Stroke Treatment Offers Hope To Severe Stroke Patients". Medical Daily. Archived from the original on 2015-10-28. Retrieved 2017-11-08.
  12. "Effectiveness of new stroke treatment confirmed". Science Daily. 2015-04-17. Archived from the original on 2015-04-20. Retrieved 2017-11-08.
  13. Saver JL, Goyal M, Bonafe A, Diener HC, Levy EI, Pereira VM, Albers GW, Cognard C, Cohen DJ, Hacke W, Jansen O, Jovin TG, Mattle HP, Nogueira RG, Siddiqui AH, Yavagal DR, Baxter BW, Devlin TG, Lopes DK, Reddy VK, du Mesnil de Rochemont R, Singer OC, Jahan R (June 2015). "Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke" (PDF). N. Engl. J. Med. 372 (24): 2285–95. doi:10.1056/NEJMoa1415061. PMID 25882376.
  14. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG (January 2018). "Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct". N. Engl. J. Med. 378 (1): 11–21. doi:10.1056/NEJMoa1706442. PMID 29129157.
  15. Cherian J, Srinivasan V, Froehler MT, Grossberg JA, Cawley CM, Hanel RA, Puri A, Dumont T, Ducruet AF, Albuquerque F, Arthur A, Cheema A, Spiotta A, Anadani M, Lopes D, Saied A, Kim L, Kelly CM, Chen PR, Mocco J, De Leacy R, Powers CJ, Grandhi R, Fargen KM, Chen SR, Johnson JN, Lam S, Kan P (September 2019). "Flow Diversion for Treatment of Intracranial Aneurysms in Pediatric Patients: Multicenter Case Series". Neurosurgery. 87: 53–62. doi:10.1093/neuros/nyz380. PMID 31557290.
  16. Brahimaj, BC; Keigher, K; Lopes, DK (2019). "Transvenous arteriovenous malformation embolization". Journal of NeuroInterventional Surgery. 12 (3): 332. doi:10.1136/neurintsurg-2019-015515. PMID 31862831. S2CID 209434543.
  17. Ughi GJ, Marosfoi MG, King RM, Caroff J, Peterson LM, Duncan BH, Langan ET, Collins A, Leporati A, Rousselle S, Lopes DK, Gounis MJ, Puri AS (July 2020). "A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy". Nature Communications. 11 (1): 3851. doi:10.1038/s41467-020-17702-7. PMC 7395105. PMID 32737314.
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