Dipeptidase 3

Dipeptidase 3 (DPEP3) is a protein that in humans is encoded by the DPEP3 gene.[5]

DPEP3
Identifiers
AliasesDPEP3, MBD3, dipeptidase 3
External IDsOMIM: 609926 MGI: 1919104 HomoloGene: 23357 GeneCards: DPEP3
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16q22.1Start67,975,663 bp[1]
End67,980,549 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

64180

71854

Ensembl

ENSG00000141096

ENSMUSG00000031898

UniProt

Q9H4B8

Q9DA79

RefSeq (mRNA)

NM_022357
NM_001129758
NM_001370198

NM_027960

RefSeq (protein)

NP_001123230
NP_001357127

NP_082236

Location (UCSC)Chr 16: 67.98 – 67.98 MbChr 8: 105.97 – 105.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a membrane-bound glycoprotein from the family of dipeptidases (EC 3.4.13.19) involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family, DPEP2. Alternatively spliced transcript variants that encode different isoforms have been found for this gene.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000141096 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000031898 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB Journal. 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806. S2CID 15252871.
  6. "Entrez Gene: Dipeptidase 3".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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