Drebrin-like

Drebrin-like protein is a protein that in humans is encoded by the DBNL gene.[5][6]

DBNL
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDBNL, ABP1, HIP-55, HIP55, SH3P7, Drebrin-like, drebrin like
External IDsOMIM: 610106 MGI: 700006 HomoloGene: 8468 GeneCards: DBNL
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7p13Start44,044,640 bp[1]
End44,069,456 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

28988

13169

Ensembl

ENSG00000136279

ENSMUSG00000020476

UniProt

Q9UJU6

Q62418

RefSeq (mRNA)

NM_001146308
NM_001146309
NM_013810

RefSeq (protein)

NP_001139780
NP_001139781
NP_038838

Location (UCSC)Chr 7: 44.04 – 44.07 MbChr 11: 5.79 – 5.8 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

Drebrin-like has been shown to interact with Cyclin-dependent kinase 4,[7] MAP4K1[8] and ZAP-70.[9]

References

  1. GRCh38: Ensembl release 89: ENSG00000136279 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000020476 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lee CG, Morse HC, Kay BK, Kozak CA (May 1999). "Genetic mapping of eight SH3 domain genes on seven mouse chromosomes". Mamm Genome. 10 (4): 402–4. doi:10.1007/s003359901011. PMID 10087302. S2CID 11371043.
  6. "Entrez Gene: DBNL drebrin-like".
  7. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  8. Ensenat D, Yao Z, Wang XS, Kori R, Zhou G, Lee SC, Tan TH (Nov 1999). "A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1". J. Biol. Chem. 274 (48): 33945–50. doi:10.1074/jbc.274.48.33945. PMID 10567356.
  9. Han J, Kori R, Shui JW, Chen YR, Yao Z, Tan TH (Dec 2003). "The SH3 domain-containing adaptor HIP-55 mediates c-Jun N-terminal kinase activation in T cell receptor signaling". J. Biol. Chem. 278 (52): 52195–202. doi:10.1074/jbc.M305026200. PMID 14557276.

Further reading


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