ELAC1

ELAC1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3ZWF
Identifiers
Aliases	ELAC1, D29, elaC ribonuclease Z 1
External IDs	OMIM: 608079 MGI: 1890495 HomoloGene: 10272 GeneCards: ELAC1
Gene location (Human)
Chr.	Chromosome 18 (human)[1]
End	50,988,121 bp[1]
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)[2]
End	73,754,479 bp[2]
RNA expression pattern
	More reference expression data
Gene ontology
Molecular function	• nuclease activity; • endonuclease activity; • 3'-tRNA processing endoribonuclease activity; • hydrolase activity; • metal ion binding; • endoribonuclease activity, producing 5'-phosphomonoesters;
Cellular component	• cytoplasm; • cytosol; • cell nucleus;
Biological process	• tRNA 3'-trailer cleavage; • RNA phosphodiester bond hydrolysis, endonucleolytic; • tRNA processing; • tRNA 3'-trailer cleavage, endonucleolytic;
	Sources:Amigo / QuickGO
Orthologs
	55520
	114615
	ENSG00000141642
	ENSMUSG00000036941
	Q9H777
	Q8VEB6
	NM_018696
	NM_053255
	NP_061166
	NP_444485
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc phosphodiesterase ELAC protein 1 is an enzyme that in humans is encoded by the ELAC1 gene.[5][6]

References

GRCh38: Ensembl release 89: ENSG00000141642 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000036941 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Takaku H, Minagawa A, Takagi M, Nashimoto M (Apr 2003). "A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease". Nucleic Acids Res. 31 (9): 2272–8. doi:10.1093/nar/gkg337. PMC 154223. PMID 12711671.
"Entrez Gene: ELAC1 elaC homolog 1 (E. coli)".

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yanaihara N, Kohno T, Takakura S, et al. (2001). "Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus". Genomics. 72 (2): 169–79. doi:10.1006/geno.2000.6454. PMID 11401430.
Tavtigian SV, Simard J, Teng DH, et al. (2001). "A candidate prostate cancer susceptibility gene at chromosome 17p". Nat. Genet. 27 (2): 172–80. doi:10.1038/84808. PMID 11175785. S2CID 7889550.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000141642 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000036941 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12711671-5] Takaku H, Minagawa A, Takagi M, Nashimoto M (Apr 2003). "A candidate prostate cancer susceptibility gene encodes tRNA 3' processing endoribonuclease". Nucleic Acids Res. 31 (9): 2272–8. doi:10.1093/nar/gkg337. PMC 154223. PMID 12711671.

[entrez-6] "Entrez Gene: ELAC1 elaC homolog 1 (E. coli)".

ELAC1

References

Further reading