EPB41L3

Band 4.1-like protein 3 is a protein that in humans is encoded by the EPB41L3 gene.[5][6][7]

EPB41L3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEPB41L3, 4.1B, DAL-1, DAL1, erythrocyte membrane protein band 4.1 like 3
External IDsOMIM: 605331 MGI: 103008 HomoloGene: 49308 GeneCards: EPB41L3
Gene location (Human)
Chr.Chromosome 18 (human)[1]
Band18p11.31Start5,392,381 bp[1]
End5,630,700 bp[1]
RNA expression pattern




More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23136

13823

Ensembl

ENSG00000082397

ENSMUSG00000024044

UniProt

Q9Y2J2

Q9WV92

RefSeq (mRNA)

NM_001281533
NM_001281534
NM_001281535
NM_012307
NM_001330557

RefSeq (protein)

NP_001268462
NP_001268463
NP_001268464
NP_001317486
NP_036439

Location (UCSC)Chr 18: 5.39 – 5.63 MbChr 17: 69.08 – 69.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

EPB41L3 has been shown to interact with YWHAB,[8][9] YWHAH,[9] YWHAG[8][9] and Cell adhesion molecule 1.[10]

References

  1. GRCh38: Ensembl release 89: ENSG00000082397 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024044 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Peters LL, Weier HU, Walensky LD, Snyder SH, Parra M, Mohandas N, Conboy JG (Dec 1998). "Four paralogous protein 4.1 genes map to distinct chromosomes in mouse and human". Genomics. 54 (2): 348–50. doi:10.1006/geno.1998.5537. PMID 9828140.
  6. Tran YK, Bögler O, Gorse KM, Wieland I, Green MR, Newsham IF (Jan 1999). "A novel member of the NF2/ERM/4.1 superfamily with growth suppressing properties in lung cancer". Cancer Research. 59 (1): 35–43. PMID 9892180.
  7. "Entrez Gene: EPB41L3 erythrocyte membrane protein band 4.1-like 3".
  8. Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  9. Yu T, Robb VA, Singh V, Gutmann DH, Newsham IF (Aug 2002). "The 4.1/ezrin/radixin/moesin domain of the DAL-1/Protein 4.1B tumour suppressor interacts with 14-3-3 proteins". The Biochemical Journal. 365 (Pt 3): 783–9. doi:10.1042/BJ20020060. PMC 1222735. PMID 11996670.
  10. Yageta M, Kuramochi M, Masuda M, Fukami T, Fukuhara H, Maruyama T, Shibuya M, Murakami Y (Sep 2002). "Direct association of TSLC1 and DAL-1, two distinct tumor suppressor proteins in lung cancer". Cancer Research. 62 (18): 5129–33. PMID 12234973.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q9Y2J2 (Band 4.1-like protein 3) at the PDBe-KB.


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