EPS8L3

Epidermal growth factor receptor kinase substrate 8-like protein 3 is an enzyme that in humans is encoded by the EPS8L3 gene.[5][6]

EPS8L3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEPS8L3, EPS8R3, EPS8 like 3, HYPT5
External IDsOMIM: 614989 MGI: 2139743 HomoloGene: 15878 GeneCards: EPS8L3
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1p13.3Start109,750,080 bp[1]
End109,764,027 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

79574

99662

Ensembl

ENSG00000198758

ENSMUSG00000040600

UniProt

Q8TE67

Q91WL0

RefSeq (mRNA)

NM_024526
NM_133181
NM_139053
NM_001319952

NM_133867

RefSeq (protein)

NP_001306881
NP_078802
NP_573444
NP_620641

NP_598628

Location (UCSC)Chr 1: 109.75 – 109.76 MbChr 3: 107.88 – 107.89 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000198758 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000040600 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C (Mar 2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure". Genomics. 81 (2): 234–44. doi:10.1016/S0888-7543(03)00002-8. PMID 12620401.
  6. "Entrez Gene: EPS8L3 EPS8-like 3".

Further reading


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