ERLEC1

ERLEC1
Identifiers
Aliases	ERLEC1, C2orf30, CIM, CL24936, CL25084, HEL117, XTP3-B, XTP3TPB, endoplasmic reticulum lectin 1
External IDs	OMIM: 611229 MGI: 1914003 HomoloGene: 9247 GeneCards: ERLEC1
Gene location (Human)
Chr.	Chromosome 2 (human)[1]
End	53,818,819 bp[1]
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)[2]
End	30,954,335 bp[2]
Gene ontology
Molecular function	• unfolded protein binding; • GO:0001948 protein binding;
Cellular component	• endoplasmic reticulum lumen; • endoplasmic reticulum quality control compartment; • endoplasmic reticulum;
Biological process	• ERAD pathway; • negative regulation of retrograde protein transport, ER to cytosol; • transmembrane transport; • ubiquitin-dependent ERAD pathway; • retrograde protein transport, ER to cytosol;
	Sources:Amigo / QuickGO
Orthologs
	27248
	66753
	ENSG00000068912
	ENSMUSG00000020311
	Q96DZ1
	Q8VEH8
	NM_001127397; NM_001127398; NM_015701
	NM_025745
	NP_001120869; NP_001120870; NP_056516
	NP_080021
	Wikidata
View/Edit Human	View/Edit Mouse

Endoplasmic reticulum lectin 1 is a protein that in humans is encoded by the ERLEC1 gene.[5][6][7][8][9]

References

GRCh38: Ensembl release 89: ENSG00000068912 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000020311 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Cruciat CM, Hassler C, Niehrs C (2006). "The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition". J. Biol. Chem. 281 (18): 12986–93. doi:10.1074/jbc.M511872200. PMID 16531414.
Christianson JC, Shaler TA, Tyler RE, Kopito RR (2008). "OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD". Nat. Cell Biol. 10 (3): 272–82. doi:10.1038/ncb1689. PMC 2757077. PMID 18264092.
"Entrez Gene: C2orf30 chromosome 2 open reading frame 30".

Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.

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