ERLIN1

ERLIN1
Identifiers
Aliases	ERLIN1, C10orf69, Erlin-1, KE04, KEO4, SPFH1, SPG62, ER lipid raft associated 1
External IDs	OMIM: 611604 MGI: 2387613 HomoloGene: 4716 GeneCards: ERLIN1
Gene location (Human)
Chr.	Chromosome 10 (human)[1]
End	100,186,033 bp[1]
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)[2]
End	44,069,785 bp[2]
Gene ontology
Molecular function	• cholesterol binding; • GO:0001948 protein binding; • lipid binding; • ubiquitin protein ligase binding;
Cellular component	• integral component of membrane; • membrane; • endoplasmic reticulum; • endoplasmic reticulum membrane; • macromolecular complex;
Biological process	• SREBP signaling pathway; • steroid metabolic process; • cholesterol metabolic process; • negative regulation of cholesterol biosynthetic process; • negative regulation of fatty acid biosynthetic process; • lipid metabolism; • ubiquitin-dependent ERAD pathway; • transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	10613
	226144
	ENSG00000107566
	ENSMUSG00000025198
	O75477
	Q91X78
NM_001100626; NM_001347856; NM_001347857; NM_001347858; NM_001347859;
	NM_001347860; NM_001347861; NM_006459
	NM_001164359; NM_001164360; NM_145502
NP_001094096; NP_001334785; NP_001334786; NP_001334787; NP_001334788;
	NP_001334789; NP_001334790; NP_006450
	NP_001157831; NP_001157832; NP_663477
	Wikidata
View/Edit Human	View/Edit Mouse

Erlin-1 is a protein that in humans is encoded by the ERLIN1 gene.[5][6][7]

References

GRCh38: Ensembl release 89: ENSG00000107566 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000025198 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Li N, Huang X, Zhao Z, Chen G, Zhang W, Cao X (Feb 2001). "Identification and characterization of a novel gene KE04 differentially expressed by activated human dendritic cells". Biochem Biophys Res Commun. 279 (2): 487–93. doi:10.1006/bbrc.2000.3935. PMID 11118313.
Browman DT, Resek ME, Zajchowski LD, Robbins SM (Jul 2006). "Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER". J Cell Sci. 119 (Pt 15): 3149–60. doi:10.1242/jcs.03060. PMID 16835267.
"Entrez Gene: ERLIN1 ER lipid raft associated 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000107566 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025198 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11118313-5] Li N, Huang X, Zhao Z, Chen G, Zhang W, Cao X (Feb 2001). "Identification and characterization of a novel gene KE04 differentially expressed by activated human dendritic cells". Biochem Biophys Res Commun. 279 (2): 487–93. doi:10.1006/bbrc.2000.3935. PMID 11118313.

[pmid16835267-6] Browman DT, Resek ME, Zajchowski LD, Robbins SM (Jul 2006). "Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER". J Cell Sci. 119 (Pt 15): 3149–60. doi:10.1242/jcs.03060. PMID 16835267.

[entrez-7] "Entrez Gene: ERLIN1 ER lipid raft associated 1".

ERLIN1

References

Further reading