Expressome

Expressome may refer to:

  • A supramolecular complex consisting of RNA polymerase and a trailing ribosome linked by a shared mRNA. The expressome complex mediates a mechanism of gene expression regulation termed transcription-translation coupling.[1][2][3]
  • The whole set of gene expression in a cell, tissue, organ, organisms, and species. Expressome is a slightly larger concept than transcriptome. The transcriptome is the set of transcripts, while expressome includes transcripts, proteins and other ligands (abundance or concentration).

See also

References
  1. Kohler, R.; Mooney, R. A.; Mills, D. J.; Landick, R. & Cramer, P. (2017). "Architecture of a transcribing-translating expressome". Science. doi:10.1126/science.aal3059. PMC 5528865. PMID 28408604.
  2. Webster, M. W.; Takacs, M.; Zhu, C.; Vidmar, V.; Eduljee, A.; Abdelkareem, M. & Weixlbaumer, A. (2020). "Structural basis of transcription-translation coupling and collision in bacteria". Science. doi:10.1126/science.abb5036. PMID 32820062.
  3. O'Reilly, F. J.; Xue, L.; Graziadei, A.; Sinn, L.; Lenz, S.; Tegunov, D.; Blötz, C.; Singh, N.; Hagen, W.; Cramer, P.; Stülke, J.; Mahamid, J. & Rappsilber, J. (2020). "In-cell architecture of an actively transcribing-translating expressome". Science. doi:10.1126/science.abb3758. hdl:21.11116/0000-0006-D30E-D. PMID 32732422.
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