FOXQ1

FOXQ1
Identifiers
Aliases	FOXQ1, HFH1, forkhead box Q1
External IDs	OMIM: 612788 MGI: 1298228 HomoloGene: 7359 GeneCards: FOXQ1
Gene location (Human)
Chr.	Chromosome 6 (human)[1]
End	1,314,758 bp[1]
Gene ontology
Molecular function	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • sequence-specific DNA binding; • DNA binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• cell nucleus;
Biological process	• hair follicle morphogenesis; • regulation of transcription, DNA-templated; • transcription, DNA-templated; • negative regulation of transcription from RNA polymerase II promoter; • anatomical structure morphogenesis; • cell differentiation; • regulation of transcription from RNA polymerase II promoter; • negative regulation of neuron apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	94234
	15220
	ENSG00000164379
	ENSMUSG00000038415
	Q9C009
	O70220
	NM_033260
	NM_008239
	NP_150285
	NP_032265
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box Q1 is a protein that in humans is encoded by the FOXQ1 gene. [4]

Function

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).

References

GRCh38: Ensembl release 89: ENSG00000164379 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Entrez Gene: Forkhead box Q1". Retrieved 2016-03-14.

FOXQ1

Function

References

Further reading