Fetal thrombotic vasculopathy

Fetal thrombotic vasculopathy is a chronic disorder characterized by thrombosis in the fetus leading to vascular obliteration and hypoperfusion.

Fetal thrombotic vasculopathy
Intermediate magnification micrograph of the placental disc showing a thrombosed fetal vein, as may be seen in fetal thrombotic vasculopathy. H&E stain.
SpecialtyPathology

It is associated with cerebral palsy and stillbirth.[1]

It is more common in women who have diabetes mellitus.

Diagnosis

It can be diagnosed by histomorphologic examination of the placenta and is characterized by fetal vessel thrombosis and clustered fibrotic chorionic villi without blood vessels.

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See also

References
  1. Kraus, FT.; Acheen, VI. (Jul 1999). "Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy". Hum Pathol. 30 (7): 759–69. PMID 10414494.
Classification
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