Fetuin-B

Fetuin-B is a protein that in humans is encoded by the FETUB gene.[5][6]

FETUB
Identifiers
AliasesFETUB, 16G2, Gugu, IRL685, fetuin B
External IDsOMIM: 605954 MGI: 1890221 HomoloGene: 8660 GeneCards: FETUB
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q27.3Start186,635,969 bp[1]
End186,653,141 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

26998

59083

Ensembl

ENSG00000090512

ENSMUSG00000022871

UniProt

Q9UGM5

Q9QXC1

RefSeq (mRNA)

NM_001083904
NM_001083905
NM_021564

RefSeq (protein)

NP_001077373
NP_001077374
NP_067539

Location (UCSC)Chr 3: 186.64 – 186.65 MbChr 16: 22.92 – 22.94 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the fetuin family, part of the cystatin superfamily of cysteine protease inhibitors. Fetuins have been implicated in several diverse functions, including osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors, and response to systemic inflammation. This protein may be secreted by cells.[6]

See also

  • Fetuin-A (alpha-2-HS-glycoprotein)

References

  1. GRCh38: Ensembl release 89: ENSG00000090512 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022871 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Olivier E, Soury E, Ruminy P, Husson A, Parmentier F, Daveau M, Salier JP (Jan 2001). "Fetuin-B, a second member of the fetuin family in mammals". Biochem J. 350 Pt 2 (2): 589–97. doi:10.1042/0264-6021:3500589. PMC 1221288. PMID 10947975.
  6. "Entrez Gene: FETUB fetuin B".

Further reading


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