GKN1

Gastrokine-1 is a protein that in humans is encoded by the GKN1 gene.[5][6][7]

GKN1
Identifiers
AliasesGKN1, AMP18, BRICD1, CA11, FOV, foveolin, gastrokine 1
External IDsOMIM: 606402 MGI: 1913533 HomoloGene: 10487 GeneCards: GKN1
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p13.3Start68,974,573 bp[1]
End68,980,980 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

56287

66283

Ensembl

ENSG00000169605

ENSMUSG00000030050

UniProt

Q9NS71

Q9CR36

RefSeq (mRNA)

NM_019617

NM_025466

RefSeq (protein)

NP_062563

NP_079742

Location (UCSC)Chr 2: 68.97 – 68.98 MbChr 6: 87.35 – 87.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is found to be down-regulated in human gastric cancer tissue as compared to normal gastric mucosa.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000169605 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030050 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Martin TE, Powell CT, Wang Z, Bhattacharyya S, Walsh-Reitz MM, Agarwal K, Toback FG (August 2003). "A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa" (PDF). American Journal of Physiology. Gastrointestinal and Liver Physiology. 285 (2): G332-43. doi:10.1152/ajpgi.00453.2002. PMID 12851218. S2CID 2860022.
  6. Shiozaki K, Nakamori S, Tsujie M, Okami J, Yamamoto H, Nagano H, et al. (October 2001). "Human stomach-specific gene, CA11, is down-regulated in gastric cancer". International Journal of Oncology. 19 (4): 701–7. doi:10.3892/ijo.19.4.701. PMID 11562744.
  7. "Entrez Gene: GKN1 gastrokine 1".

Further reading

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