GRIP1 (gene)

Glutamate receptor-interacting protein 1 is a protein that in humans is encoded by the GRIP1 gene.[5][6]

GRIP1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGRIP1, GRIP, glutamate receptor interacting protein 1, FRASRS3
External IDsOMIM: 604597 MGI: 1921303 HomoloGene: 12938 GeneCards: GRIP1
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q14.3Start66,347,431 bp[1]
End67,069,162 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

23426

74053

Ensembl

ENSG00000155974

ENSMUSG00000034813

UniProt

Q9Y3R0

Q925T6

RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 12: 66.35 – 67.07 MbChr 10: 119.45 – 120.09 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

GRIP1 (gene) has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000155974 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000034813 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains". Neuron. 22 (3): 511–24. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531.
  6. "Entrez Gene: GRIP1 glutamate receptor interacting protein 1".
  7. Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM, Dev KK (May 2002). "The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs". J. Biol. Chem. 277 (18): 15221–4. doi:10.1074/jbc.C200112200. PMID 11891216.
  8. Hirbec H, Francis JC, Lauri SE, Braithwaite SP, Coussen F, Mulle C, Dev KK, Coutinho V, Meyer G, Isaac JT, Collingridge GL, Henley JM, Couthino V (February 2003). "Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP". Neuron. 37 (4): 625–38. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502. PMID 12597860.
  9. Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (June 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157. S2CID 16571878.

Further reading

  • Overview of all the structural information available in the PDB for UniProt: Q9Y3R0 (Human Glutamate receptor-interacting protein) at the PDBe-KB.
  • Overview of all the structural information available in the PDB for UniProt: Q925T6 (Mouse Glutamate receptor-interacting protein) at the PDBe-KB.


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