Galactose-3-O-sulfotransferase

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Galactose-3-O-sulfotransferase
Identifiers
Symbol	Gal-3-0_sulphotransfrase
Pfam	PF06990
InterPro	IPR009729
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Galactose-3-O-sulfotransferases is a family of several mammalian galactose-3-O-sulfotransferase proteins. Gal-3-O-sulfotransferase is thought to play a critical role in 3'-sulfation of N-acetyllactosamine in both O- and N-glycans.[1]

Human proteins from this family

GAL3ST1; GAL3ST2; GAL3ST3; GAL3ST4; GP3ST;

References

Suzuki A, Fukuda M, Suzuki M, Hiraoka N, Angata K, Misra AK, Mcauliffe J, Hindsgaul O (2001). "Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans". J. Biol. Chem. 276 (26): 24388–24395. doi:10.1074/jbc.M103135200. PMID 11323440.

This article incorporates text from the public domain Pfam and InterPro: IPR009729

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[PUB00012964-1] Suzuki A, Fukuda M, Suzuki M, Hiraoka N, Angata K, Misra AK, Mcauliffe J, Hindsgaul O (2001). "Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans". J. Biol. Chem. 276 (26): 24388–24395. doi:10.1074/jbc.M103135200. PMID 11323440.

Transferases: sulfur-containing group (EC 2.8)
2.8.1: Sulfurtransferases	Thiosulfate sulfurtransferase Rhodanese 3-mercaptopyruvate sulfurtransferase thiosulfate—thiol sulfurtransferase tRNA sulfurtransferase thiosulfate—dithiol sulfurtransferase biotin synthase cysteine desulfurase
2.8.2: Sulfotransferases	Alcohol sulfotransferase Tyrosylprotein sulfotransferase Aryl sulfotransferase
2.8.3: CoA-transferases	Propionate CoA-transferase
2.8.4: Alkylthio	Coenzyme-B sulfoethylthiotransferase

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)