Gamma-D-Glutamyl-meso-diaminopimelate peptidase
Gamma-D-glutamyl-meso-diaminopimelate peptidase (EC 3.4.19.11, endopeptidase I, gamma-D-glutamyldiaminopimelate endopeptidase, gamma-D-glutamyl-L-meso-diaminopimelate peptidoglycan hydrolase, gamma-glutamyl-L-meso-diaminopimelyl endopeptidase, gamma-D-glutamyl-meso-diaminopimelate endopeptidase, gamma-D-glutamyl-meso-diaminopimelic peptidoglycan hydrolase, gamma-D-glutamyl-meso-diaminopimelic endopeptidase, gamma-D-glutamyl-meso-D-aminopimelic endopeptidase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Hydrolysis of gamma-D-glutamyl bonds to the L-terminus (position 7) of meso-diaminopimelic acid (meso-A2pm) in 7-(L-Ala-gamma-D-Glu)-meso-A2pm and 7-(L-Ala-gamma-D-Glu)-7-(D-Ala)-meso-A2pm. It is required that the D-terminal amino and carboxy groups of meso-A2pm are unsubstituted
| Gamma-D-glutamyl-meso-diaminopimelate peptidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.4.19.11 | ||||||||
| CAS number | 62572-28-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This metallopeptidase is isolate from Bacillus sphaericus.
References
- Arminjon F, Guinand M, Vacheron MJ, Michel G (March 1977). "Specificity profiles of the membrane-bound gamma-D-glutamyl-(L)meso-diaminopimelateendopeptidase and LD-carboxypeptidase from Bacillus sphaericus 9602". European Journal of Biochemistry. 73 (2): 557–65. doi:10.1111/j.1432-1033.1977.tb11351.x. PMID 849747.
- Garnier M, Vacheron MJ, Guinand M, Michel G (May 1985). "Purification and partial characterization of the extracellular gamma-D-glutamyl-(L)meso-diaminopimelate endopeptidase I, from Bacillus sphaericus NCTC 9602". European Journal of Biochemistry. 148 (3): 539–43. doi:10.1111/j.1432-1033.1985.tb08873.x. PMID 3922755.
- Hourdou ML, Guinand M, Vacheron MJ, Michel G, Denoroy L, Duez C, Englebert S, Joris B, Weber G, Ghuysen JM (June 1993). "Characterization of the sporulation-related gamma-D-glutamyl-(L)meso-diaminopimelic-acid-hydrolysing peptidase I of Bacillus sphaericus NCTC 9602 as a member of the metallo(zinc) carboxypeptidase A family. Modular design of the protein". The Biochemical Journal. 292 (2): 563–70. doi:10.1042/bj2920563. PMC 1134247. PMID 8503890.
External links
- Gamma-D-glutamyl-meso-diaminopimelate+peptidase at the US National Library of Medicine Medical Subject Headings (MeSH)
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