HAPLN1

Hyaluronan and proteoglycan link protein 1 is a protein that in humans is encoded by the HAPLN1 gene.[5][6][7]

HAPLN1
Identifiers
AliasesHAPLN1, CRTL1, CRT1, hyaluronan and proteoglycan link protein 1
External IDsOMIM: 115435 MGI: 1337006 HomoloGene: 1420 GeneCards: HAPLN1
Gene location (Human)
Chr.Chromosome 5 (human)[1]
Band5q14.3Start83,637,805 bp[1]
End83,720,855 bp[1]
RNA expression pattern


More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

1404

12950

Ensembl

ENSG00000145681

ENSMUSG00000021613

UniProt

P10915

Q9QUP5

RefSeq (mRNA)

NM_001884

NM_013500

RefSeq (protein)

NP_001875

NP_038528

Location (UCSC)Chr 5: 83.64 – 83.72 MbChr 13: 89.54 – 89.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

HAPLN1 has been shown to interact with Versican.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000145681 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000021613 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Osborne-Lawrence SL, Sinclair AK, Hicks RC, Lacey SW, Eddy RL, Byers MG, et al. (November 1990). "Complete amino acid sequence of human cartilage link protein (CRTL1) deduced from cDNA clones and chromosomal assignment of the gene". Genomics. 8 (3): 562–7. doi:10.1016/0888-7543(90)90044-U. PMID 2286376.
  6. Dudhia J, Hardingham TE (March 1990). "The primary structure of human cartilage link protein". Nucleic Acids Research. 18 (5): 1292. doi:10.1093/nar/18.5.1292. PMC 330454. PMID 2320422.
  7. "Entrez Gene: HAPLN1 hyaluronan and proteoglycan link protein 1".
  8. Matsumoto K, Shionyu M, Go M, Shimizu K, Shinomura T, Kimata K, Watanabe H (October 2003). "Distinct interaction of versican/PG-M with hyaluronan and link protein". The Journal of Biological Chemistry. 278 (42): 41205–12. doi:10.1074/jbc.M305060200. PMID 12888576.

Further reading


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