Hendrik Streeck

Hendrik Streeck (born 7 August 1977 in Göttingen) is a German researcher of human immunodeficiency virus, epidemiologist and clinical trialist. He is professor of virology and the director of the Institute of Virology and HIV Research at the University Bonn.[1][2]

For the painter, see Hendrick van Streeck.
Hendrik Streeck
Born (1977-08-07) August 7, 1977
Göttingen, Germany
OccupationScientist, physician, clinical trialist
OrganizationInstitute for HIV Research

Early life and education

Streeck studied medicine at the Charite University, Berlin. After his graduation he started to work as a postdoctoral fellow at the Ragon Institute of Massachusetts General Hospital, the Massachusetts Institute of Technology, and Harvard Medical School and obtained his PhD from the University of Bonn, and part-time at the Partners AIDS Research Center, Massachusetts General Hospital and Harvard Medical School.

Career

In 2009 Streeck was promoted to Instructor in Medicine and in 2011 to Assistant Professor at Harvard Medical School. In September 2012 he was recruited to the United States Military HIV Research Program, Bethesda, where he became the Chief of the Cellular Immunology Section as well as Assistant Professor at the Uniformed Services University of Health Sciences and adjunct faculty of the Bloomberg School of Public Health, Johns Hopkins University.[3] In 2015 he became the Chair for Medical Biology at the University Duisburg-Essen and founded the Institute for HIV Research in the same year,[4][5][6][7] though he still maintains the status of "visiting scientist" with the US Military HIV Research Program.

In 2018, Streeck was appointed to the advisory board of the German AIDS Foundation (Deutsche AIDS Stiftung).[8] In April 2020, he was appointed by Minister-President Armin Laschet of North Rhine-Westphalia to a 12-member expert group to advise on economic and social consequences of the COVID-19 pandemic in Germany.[9]

HIV research

Under Streek's direction the Institute for HIV Research works on several prevention methods against HIV including the development and feasibility of HIV vaccines as well as pre-exposure prophylaxis.[10][11][12] A particular focus for HIV vaccine development is to understand how T follicular helper (Tfh) cells can drive protective antibody responses during the germinal center reaction. Further research areas of the institute include understanding why some co-morbidities, such as cancer or cardiovascular diseases, are more prone to develop in chronic HIV infection and whether strategies can be developed to suppress HIV viral loads in the absence of antiretroviral therapy. Some of these studies are being performed in Maputo, Mozambique, where he leads a PhD sandwich program with the Instituto Nacionale de Saude to train and retain young physician scientists.[13]

Sexually transmitted infections research

Streeck actively investigates the epidemiology, novel prevention and treatment options of other sexually transmitted infections.[14] Currently, he conducts the largest systematic study for sexually transmitted infections in Germany, which seeks to understand who is becoming infected with which sexually transmitted infection.

In January 2019 the study was expanded to other European countries including France, Italy, Spain, Poland and Hungary under the name STIPnet study. In parallel, a European network to prevent human immunodeficiency virus and sexually transmitted infections will be established[15][16] He has been nominated as the co-chair of International AIDS conference IAS 2021 in Berlin.[17]

Coronavirus research

In early April 2020, Streeck and his team reported with reference to their COVID-19 Case-Cluster-Study that they had "carried out an intensive search of the home of a family infected with the coronavirus but found no trace of it on surfaces."[18]

Awards
  • 2015 – 15 HIV Advocates to Watch in 2015[19]
  • 2014 – People Magazine “Sexiest Scientist” 2014[20]
  • 2011 – Young Investigator Award, Collaborative AIDS Vaccine Discovery Bill and Melinda Gates Foundation
  • 2010 – Young Investigator Award, 17th CROI, San Francisco, CA
  • 2009 – Biennial German AIDS Award
  • 2009 – New Investigator Award, AIDS Vaccine Conference, Paris
  • 2009 – New Investigator Award, 16th CROI, Montreal, Canada
  • 2008 – Young Investigator Award, World AIDS Conference, Mexico City
  • 2008 – New Investigator Award, AIDS Vaccine Conference, Cape Town
  • 2008 – NIH Scholarship 2008, HIV-Vaccine, Keystone, Banff
  • 2008 – Young Investigator Award, 15th CROI, Boston, MA
  • 2007 – Young Investigator Award, 14th CROI, Los Angeles, CA
  • 2006 – Young Investigator Award, 13th CROI, Denver, CO
  • 2006 – Young Investigator Award, World AIDS Conference, Toronto
  • 2005 – Young Investigator Award, HIV-Pathogenesis, Keystone, Banff

Associations
  • American Society for Microbiology
  • American Association of Immunologists
  • German Association of University Professors (Deutscher Hochschulverband)

Works

Books/Chapters
  • H. Streeck, G. Alter: "Immune Responses to Viral Infections." In: D. D. Richman, J. Whitley, F. G. Hayden: Clinical virology. 4. edition. ASM Press, 2016, ISBN 978-1-55581-942-2
  • H. Streeck: Bug Attack (The Adventures of Damien the CD4 Cell & his Friends).Band 1, ISBN 1-5052-4534-6. (A children's book for age 3–6 years, English)

Publications (selection)
  • B. T. Schultz, A. F. Oster, F. Pissani, J. E. Teigler, G. Kranias, G. Alter, M. Marovich, M. A. Eller, U. Dittmer, M. L. Robb, J. H. Kim, N. L. Michael, D. Bolton, H. Streeck: "Circulating HIV-Specific Interleukin-21+CD4+ T Cells Represent Peripheral Tfh Cells with Antigen-Dependent Helper Functions." In: Immunity. 2016.
  • F. Pissani, H. Streeck: "Emerging concepts on T follicular helper cell dynamics in HIV infection" In: Trends in Immunology. 35(6), Jun 2014, S. 278–286.
  • S. Ranasinghe, S. Cutler, I. Davis, R. Lu, D. Z. Soghoian, Y. Qi, J. Sidney, G. Kranias, M. D. Flanders, M. Lindqvist, B. Kuhl, G. Alter, S. G. Deeks, B. D. Walker, X. Gao, A. Sette, M. Carrington, H. Streeck: "Association of HLA-DRB1-restricted CD4⁺T cell responses with HIV immune control." In: Nature Medicine . 19(7), Jul 2013, S. 930–933.
  • M. Lindqvist, J. van Lunzen, D. Z. Soghoian, B. D. Kuhl, S. Ranasinghe, G. Kranias, M. D. Flanders, S. Cutler, N. Yudanin, M. I. Muller, I. Davis, D. Farber, P. Hartjen, F. Haag, G. Alter, J. Schulze zur Wiesch, H. Streeck: "Expansion of HIV-specific T follicular helper cells in chronic HIV infection" In: Journal of Clinical Investigation. 122(9), 4. Sep 2012, S. 3271–3280.
  • M. F. Chevalier, B. Jülg, A. Pyo, M. Flanders, S. Ranasinghe, D. Z. Soghoian, D. S. Kwon, J. Rychert, J. Lian, M. I. Muller, S. Cutler, E. McAndrew, H. Jessen, F. Pereyra, E. S. Rosenberg, M. Altfeld, B. D. Walker, H. Streeck: "HIV-1-specific interleukin-21+ CD4+ T cell responses contribute to durable viral control through the modulation of HIV-specific CD8+ T cell function." In: Journal of Virology. 85(2), Jan 2011, S. 733–741.
  • H. Streeck, B. Li, A. F. Poon, A. Schneidewind, A. D. Gladden, K. A. Power, D. Daskalakis, S. Bazner, R. Zuniga, C. Brander, E. S. Rosenberg, S. D. Frost, M. Altfeld, T. M. Allen: "Immune-driven recombination and loss of control after HIV superinfection" In: Journal of Experimental Medicine. 205(8), 4. Aug 2008, S. 1789–1796.

References
  1. Baumann, Andreas. "Universitätsklinikum Bonn: Institut für Virologie hat neuen Direktor". GA BONN (in German). Retrieved 2019-10-31.
  2. "Institute for HIV Research". Institute for HIV Research. Retrieved 2019-10-31.
  3. "MHRP Welcomes Dr. Hendrik Streeck". MHRP | Military HIV Research Program. Retrieved 2019-01-07.
  4. "Germany's first dedicated HIV research hub opens in 'exciting times' for vaccine | DW | 16.11.2016". DW.COM. Retrieved 2019-01-07.
  5. "Prof. Dr. Hendrik Streeck". HuffPost Deutschland (in German). Retrieved 2019-01-07.
  6. "Hendrik Streeck". Institute for HIV Research. Retrieved 2019-01-07.
  7. King, Mark S. (2015-01-06). "15 HIV Advocates to Watch in 2015". My Fabulous Disease. Retrieved 2019-01-07.
  8. AIDS-Stiftung, Deutsche. "HIV-Impfstoffforscher Hendrik Streeck ins Kuratorium der Deutschen AIDS-Stiftung berufen". Deutsche AIDS-Stiftung (in German). Archived from the original on 2019-01-07. Retrieved 2019-01-07.
  9. Kristian Frigelj (April 1, 2020), Zwölfköpfiges Gremium: Armin Laschet gründet „Expertenrat Corona“ Die Welt.
  10. "Professor Hendrik Streeck: "HIV vaccine would be the best solution"". Platforma. 2018-02-27. Retrieved 2019-01-07.
  11. "New HIV Cohort Study Opens In Germany". MHRP | Military HIV Research Program. Retrieved 2019-01-07.
  12. "Pre-exposure prophylaxis (PrEP) implementation, uptake and retention in Germany - results of the PRIDE study". programme.aids2018.org. Retrieved 2019-01-07.
  13. "Meldungen aus der UDE". www.uni-due.de. Retrieved 2019-01-07.
  14. "BRAHMS Info". Institute for HIV Research. Retrieved 2019-01-07.
  15. "STIPnet: European HIV & STI Prevention Network". Retrieved 2019-01-07.
  16. "Collaboration to understand the HIV & STI epidemics in Europe". www.alphagalileo.org. Retrieved 2019-01-07.
  17. Mutingwende, Byron Adonis (2019-07-25). "Prof Hendrik Streeck announced as the Local Scientific Chair of IAS 2021". Zimbabwe News Newsdzezimbabwe. Retrieved 2019-08-02.
  18. "No proof coronavirus can be spread while shopping, says leading German virologist". Telegraph Media Group Limited. 2 April 2020.
  19. "15 HIV Advocates to Watch in 2015". www.hivplusmag.com. 2015-03-12. Retrieved 2019-04-07.
  20. "Sexy Men at Work". PEOPLE.com. Retrieved 2019-04-07.
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