KCTD15

Potassium channel tetramerisation domain containing 15 also known as BTB/POZ domain-containing protein KCTD15 is protein that in humans is encoded by the KCTD15 gene.[5]

KCTD15
Identifiers
AliasesKCTD15, potassium channel tetramerization domain containing 15
External IDsOMIM: 615240 MGI: 2385276 HomoloGene: 11450 GeneCards: KCTD15
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19q13.11Start33,795,933 bp[1]
End33,815,763 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

79047

233107

Ensembl

ENSG00000153885

ENSMUSG00000030499

UniProt

Q96SI1

Q8K0E1

RefSeq (mRNA)

NM_001129994
NM_001129995
NM_024076

NM_146188
NM_001360818
NM_001360820

RefSeq (protein)

NP_001123466
NP_001123467
NP_076981

NP_666300
NP_001347747
NP_001347749

Location (UCSC)Chr 19: 33.8 – 33.82 MbChr 7: 34.64 – 34.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Clinical significance

Variants of the KCTD15 gene may be associated with obesity.[6][7][8]

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000153885 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030499 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Strausberg RL, Feingold EA, Grouse LH, et al. (December 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. Thorleifsson G, Walters GB, Gudbjartsson DF, et al. (January 2009). "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity". Nat. Genet. 41 (1): 18–24. doi:10.1038/ng.274. PMID 19079260. S2CID 764409.
  7. Willer CJ, Speliotes EK, Loos RJ, et al. (January 2009). "Six new loci associated with body mass index highlight a neuronal influence on body weight regulation". Nat. Genet. 41 (1): 24–34. doi:10.1038/ng.287. PMC 2695662. PMID 19079261.
  8. Zhao J, Bradfield JP, Li M, et al. (May 2009). "The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI". Obesity (Silver Spring). 17 (12): 2254–7. doi:10.1038/oby.2009.159. PMC 2860782. PMID 19478790.

Further reading


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