Karen Duff

Karen Elizabeth Keitley Duff (born 1965) is a British scientist known for her work on Alzheimer's disease. Her most notable work focused on the development and characterization of mouse models of Alzheimer's disease amyloid deposition.[1][2] She became Centre Director of the UK Dementia Research Institute's hub at University College London in Spring 2020.[3]

Karen Duff
Born1965 (age 55–56)
Alma materUniversity of East Anglia
Queens' College, Cambridge
AwardsPotamkin Prize (2006)
Scientific career
FieldsPathology
Cell Biology
InstitutionsUniversity College London
Columbia University
New York University
University of South Florida
ThesisA study of human and murine cardiac development using molecular genetics methodology (1991)
WebsiteKaren Duff, Ph.D.

She was educated at the University of East Anglia (BSc, 1987) and completed her PhD at Queens' College, Cambridge in 1991 entitled "A study of human and murine cardiac development using molecular genetics methodology". At Cambridge she was a student of Sydney Brenner's department. She was awarded the Potamkin Prize in 2006, together with Karen Ashe and Bradley Hyman.[4] She was formerly Professor of Pathology and Cell Biology at Columbia University.[5]

She has an h-index of 89.[6]

References
  1. Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K (Jan 1998). "Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes". Nat Med. 4 (1): 97–100. doi:10.1038/nm0198-097. PMID 9427614. S2CID 22491239.CS1 maint: uses authors parameter (link)
  2. Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S (Oct 1996). "Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1". Nature. 383 (6602): 710–3. Bibcode:1996Natur.383..710D. doi:10.1038/383710a0. PMID 8878479. S2CID 4339658.CS1 maint: uses authors parameter (link)
  3. "Right drug, right patient, right time: Unravelling clinical trial failures in dementia with Professor Karen Duff". UK Dementia Research Institute. Retrieved 4 February 2021.
  4. "Karen Duff Receives Prestigious Prize for Alzheimer's Research". NYU Langone Medical Center. Retrieved 6 August 2014.
  5. "Karen Duff, Ph.D. - Professor of Pathology & Cell Biology". Columbia University. Retrieved 6 August 2014.
  6. "karen duff". Google Scholar. Retrieved 25 April 2019.
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