Leucine carboxyl methyltransferase 1

Leucine carboxyl methyltransferase 1 is an enzyme that in humans is encoded by the LCMT1 gene.[5][6]

LCMT1
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesLCMT1, LCMT, PPMT1, CGI-68, leucine carboxyl methyltransferase 1
External IDsOMIM: 610286 MGI: 1353593 HomoloGene: 41123 GeneCards: LCMT1
Gene location (Human)
Chr.Chromosome 16 (human)[1]
Band16p12.1Start25,111,731 bp[1]
End25,178,231 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

51451

30949

Ensembl

ENSG00000205629

ENSMUSG00000030763

UniProt

Q9UIC8

n/a

RefSeq (mRNA)

NM_001032391
NM_016309

NM_025304
NM_001355050

RefSeq (protein)

NP_001027563
NP_057393

n/a

Location (UCSC)Chr 16: 25.11 – 25.18 MbChr 7: 123.37 – 123.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

LCMT1 has been shown to interact with FXR2.[7]

References

  1. GRCh38: Ensembl release 89: ENSG00000205629 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030763 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (May 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Research. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
  6. "Entrez Gene: LCMT1 leucine carboxyl methyltransferase 1".
  7. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

Further reading

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